Professor
University of Rochester
Dr. Morrell earned his undergraduate degree from Brown University in 1995. He then graduated from Tufts University School of Veterinary Medicine in 2000 before beginning a comparative pathology fellowship and PhD at The Johns Hopkins University School of Medicine. Dr. Morrell then established an independent laboratory in the Department of Molecular and Comparative Pathobiology at Hopkins from 2005-2009, before moving to the University of Rochester's Aab Cardiovascular Research Institute. He is now Professor and Interim Director of the Aab CVRI at the University of Rochester.
Research in his lab is focused on the complex interface between platelets, the vasculature, and immune cells. Platelets are not only the cellular mediators of thrombosis, but also have important roles in inflammatory and immune cell responses. Ongoing and past studies by his group have examined platelet, and platelet derived inflammatory mediator interactions with both vascular and immune cells, and the impact of these interactions on tissue injury responses in disease relevant contexts. These studies have demonstrated that platelets are regulators of all aspects of inflammatory responses, including the induction of acute phase responses, innate immune cell activation and trafficking, T helper cell differentiation, and B cell development. The Morrell lab regularly uses advanced mouse models to dissect molecular interactions and vascular inflammatory signaling pathways both in vitro and in vivo, establishing it as leaders in understanding how platelets regulate vascular and immune cell homeostatic and inflammatory responses. This work continues to define many novel implications for platelet immune regulation in vascular and inflammatory disease processes.
Monday, July 11, 2022
6:30 PM – 7:30 PM
Tuesday, July 12, 2022
8:00 AM – 8:20 AM