Khalid M. Naseem, PhD

Professor
University of Leeds

Khalid Naseem is a Professor of Cardiovascular Biology in the Institute of Cardiovascular and Medtabolic Medicine at the University of Leeds (UK). The focus of research in Khalid's laboratory is identifying the molecular and cellular mechanism(s) that lead to platelet hyperactivity, which can in turn contribute to atherogenesis and atherothrombosis in the context of metabolic disorders such as dyslipidaemia and dysglycaemia. Key to the work is the role of a surface protein called cluster of differentiation 36 (CD36), a multifunctional receptor acts as a fatty acid transporter and scavenger receptor that sensors immunological and metabolic changes in the blood. Ongoing studies are examining how distinct CD36 ligands differentially control haemostasis and while also promoting pathological thrombosis is disease states.

Presentation(s):

• OC 10.1 - CD36-dependent metabolic rewiring and mitochondrial dysfunction in platelets in response to hyperlipidaemia.

  Saturday, July 9, 2022
  1:00 PM – 1:15 PM

• PB0392 - Pim kinase: A novel regulator of platelet and megakaryocyte thromboxane A2 and C-X-C-R motif receptors

  Sunday, July 10, 2022
  6:30 PM – 7:30 PM

• OC 35.2 - The role of Adenylyl Cyclase 6 in platelet cyclic-AMP signalling

  Monday, July 11, 2022
  11:00 AM – 11:15 AM

• PB0642 - The use of plasminogen activator inhibitor-1 specific Affimers as a tool to modulate fibrin clot properties and thrombosis risk

  Monday, July 11, 2022
  6:30 PM – 7:30 PM

• PB0859 - The uptake and utilisation of fatty acids by platelets.

  Monday, July 11, 2022
  6:30 PM – 7:30 PM

• SOA 28.1 - The Role of Thrombospondin-1 in Hemostasis

  Wednesday, July 13, 2022
  8:30 AM – 8:50 AM