Director of The Laboratory of Vascular Thrombosis and Inflammation
National Heart, Lung, and Blood Institute
Dr. Yogen Kanthi is a Lasker Investigator and Distinguished Scholar at the National Heart, Lung and Blood Institute in the United States, and a practicing cardiologist and vascular medicine specialist. His long-term goal as a physician scientist is to develop new treatments for highly morbid inflammatory and thrombotic diseases. He leads a clinical and translational research program at the National Institutes of Health focused on understanding the role of inflammation in thrombogenesis. Dr. Kanthi’s team made seminal observations about the inflammatory contributors to venous thrombosis including defining central roles for inflammasome activation and purinergic regulation in venous thrombosis. Dr. Kanthi's team made landmark contributions to the understanding of thromboinflammation in COVID, discovering roles for neutrophil activation and neutrophil extracellular traps in COVID, and identifying calprotectin as a serologic biomarker of respiratory failure which is now in clinical use in the EU. Dr. Kanthi’s group also made the first observation that severe COVID triggers the production of circulating pathogenic autoantibodies in patients with COVID implicated in innate immune activation, vascular inflammation, and thrombosis.
Tuesday, July 12, 2022
8:20 AM – 8:40 AM