OC 73 - Acquired Thrombocytopenias

Moderator(s)

• 

  Jorge DiPaola, MD

  Professor of Pediatrics & Molecular Genetics and Genomics
  Pediatrics
  Department of Pediatrics, School of Medicine, Washington University
  St. Louis, Missouri, United States
• 

  Nichola Cooper, MS (Cantab), MBBS, MD, FRCP, FRCPath,

  Department of Medicine
  Department of Medicine
  Hammersmith Hospital
  London, England, United Kingdom

Presentations:

• 10:15 AM – 10:30 AM

  Updated Main Study Period and Long-Term Extension (LTE) Results With Oral Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Immune Thrombocytopenia (ITP)
  

  Presenting Author: David J. J. Kuter, MD, DPhil – Hematology Division, Massachusetts General Hospital, Harvard Medical School

  Co-Author: Merlin Efraim – Multiprofile Hospital for Active Treatment Sveta Marina EAD

  Co-Author: Zane Kaplan – Monash Medical Centre

  Co-Author: Jiri Mayer – Department of Internal Medicine, Hematology and Oncology, Masaryk University Hospital

  Co-Author: Philip Choi, MBBS PhD FRACP FRCPA – Canberra Hospital

  Co-Author: Gerard A. J. Jansen – Department of Hematology, Erasmus MC, University Medical Center

  Co-Author: Vickie McDonald, MA MRCP FRCPath PhD – Barts Health NHS Trust, The Royal London Hospital

  Co-Author: Ross I. Baker, MD – Health Futures Institute, Murdoch University, Perth, Australia

  Co-Author: Robert Bird – Princess Alexandra Hospital

  Co-Author: Mamta Garg – Leicester Royal Infirmary

  Co-Author: Jaromír Gumulec – Department of Hematooncology, University Hospital Ostrava and Faculty of Medicine University of Ostrava

  Co-Author: Milan Košťál – University Hospital of Hradec Králové

  Co-Author: Terry Gernsheimer – University of Washington Medical Center

  Co-Author: Waleed Ghanima, MD – Østfold Hospital Foundation

  Co-Author: Mengjie Yao – Sanofi US Services Inc.

  Co-Author: Nichola Cooper – Hammersmith Hospital

  Co-Author: Ahmed Daak – Sanofi Genzyme
• 10:30 AM – 10:45 AM

  Phascolarctobacterium was increased in ITP and negatively correlated with platelet counts
  

  Presenting Author: Honghui Wang, PhD – The Second Affiliated Hospital of Kunming Medical University

  Co-Author: Hui Bi – The Second Affiliated Hospital of Kunming Medical University

  Co-Author: Zhou Zeping – The Second Affiliated Hospital of Kunming Medical University
• 10:45 AM – 11:00 AM

  Thrombopoietin receptor agonists (TPO-RAs) in older patients with primary immune thrombocytopenia (ITP): effective and safe? Real World Data from the UK adult ITP registry.
  

  Presenting Author: Priyanka Raheja, MBBS, MD – Royal London Hospital

  Co-Author: Haroon Miah – Queen Mary University London

  Co-Author: Atiqa Miah – Royal London Hospital

  Co-Author: Lousie Taylor – Royal London Hospital

  Co-Author: Tina T. Biss, BM BS, MRCP, FRCPath, MD – The Newcastle upon Tyne Hospitals NHS Foundation Trust

  Co-Author: Gillian Evans – East Kent Hospitals University NHS Foundation Trust

  Co-Author: Marie Scully – University College Hospitals London NHS Foundation Trust

  Co-Author: Joannes Hermans – Nottingham University Hospitals NHS Trust

  Co-Author: Scott Marshall – Sunderland Royal Hospital

  Co-Author: Mari Kilner – Northumbria Healthcare NHS Foundation Trust

  Co-Author: Rachel Rayment – Cardiff and Vale, University Hospital of Wales

  Co-Author: Lisa Robinson – County Hospital, Wye Valley NHS Trust (Hereford)

  Co-Author: Sarah Johns – Royal Cornwall Hospital

  Co-Author: Ciro Rinaldi – Pilgrim Hospital

  Co-Author: Helen Jackson – Aneurin Bevan University Health Board, Royal Gwent

  Co-Author: Sam Ackroyd – Bradford Royal Infirmary

  Co-Author: Adrian Newland – Royal London Hospital

  Co-Author: Drew Provan – Royal London Hospital

  Co-Author: Nichola Cooper – Hammersmith Hospital

  Co-Author: Vickie McDonald, MA MRCP FRCPath PhD – Barts Health NHS Trust, The Royal London Hospital
• 11:00 AM – 11:15 AM

  Characterization of a novel anti-GPVI antibody in a humanized GP6 (hGP6KI) mouse model
  

  Presenting Author: Stefano Navarro, MSc – University Hospital Würzburg

  Co-Author: Andreas Starke – University hospital Würzburg

  Co-Author: Helena Brown – University hospital Würzburg

  Co-Author: Sarah Beck, PhD – University Hospital and Rudolf Virchow Center, University of Würzburg

  Co-Author: Valerie Orth – Emfret Analytics

  Co-Author: Johan Heemskerk – Department of Biochemistry, CARIM, Maastricht University, Maastricht, the Netherlands; Synapse Research Institute Maastricht, The Netherlands

  Co-Author: Marijke Kuijpers – Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University; Thrombosis Expertise Centre, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, The Netherlands

  Co-Author: David Stegner, PhD – University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging University of Würzburg

  Co-Author: Bernhard Nieswandt – Institute of Experimental Biomedicine, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg
• 11:15 AM – 11:30 AM

  Investigations to assess Impact of Syk-inhibition on antibody-mediated desialylation: novel implications on therapy for immune thrombocytopenia
  

  Presenting Author: Anurag Singh, PhD – Institute for Clinical and Experimental Transfusion Medicine, University Hospital of Tuebingen, Tuebingen, Germany

  Co-Author: Filip Toma – ​​Institute for Clinical and Experimental Transfusion Medicine, University Hospital Tübingen

  Co-Author: Karina Althaus, MD – Institute for Clinical and Experimental Transfusion Medicine, Medical Faculty of Tuebingen, University Hospital of Tuebingen, Tuebingen, Germany

  Co-Author: Tamam Backchoul, MD – Institute for Clinical and Experimental Transfusion Medicine, Medical Faculty of Tuebingen, University Hospital of Tuebingen, Tuebingen, Germany