PB0669 - The Interobserver and Intraobserver Agreements on HEAD-US in the assessment of Hemophilic Arthropathy

Monday, July 11, 2022

6:30 PM – 7:30 PM

Location: Exhibition

Presentation Format: In-Person

Co-Author(s)

EY

Emine Yılmaz

Resident
Gazi University Faculty of Medicine, Department of Pediatric Hematology
Ankara, Ankara, Turkey

Presenting Author(s)

Zühre Kaya, MD

Professor
Gazi University Faculty of Medicine, Department of Pediatric Hematology
Ankara, Ankara, Turkey

Co-Author(s)

HS

Hasan Satış

Specialist
Gazi University Faculty of Medicine, Department of Rheumatology
Ankara, Ankara, Turkey
�A

İsmail Akdulum

Specialist
Gazi University Faculty of Medicine, Department of Radiology
Ankara, Ankara, Turkey
MY

Merve Yazol

Specialist
Gazi University Faculty of Medicine, Department of Radiology
Ankara, Ankara, Turkey
AT

Abdurrahman Tufan

Professor
Gazi University Faculty of Medicine, Department of Rheumatology
ANKARA, Ankara, Turkey
�H

Şeminur Haznedaroğlu

Professor
Gazi University Faculty of Medicine, Department of Rheumatology
Ankara, Ankara, Turkey
OK

Oznur Konuş Boyunaga

Professor
Gazi University Faculty of Medicine, Department of Radiology
Ankara, Ankara, Turkey
SK

Serap Kirkiz

Assistant Professor
Gazi University Faculty of Medicine, Department of Pediatric Hematology
Ankara, Ankara, Turkey
�K

Ülker Koçak

Professor
Gazi University Faculty of Medicine, Department of Pediatric Hematology
Ankara, Ankara, Turkey

Background: Few data are available in the evaluation of hemophilic arthropathy with HEAD-US (hemophilia early arthropathy detection with ultrasound) by different caregivers.

Aims: The purpose of this study was to evaluate the interobserver and intraobserver agreements in the assessment of hemophilic arthropathy on HEAD-US by different caregivers.

Methods: A total of 28 patients with severe hemophilia A and B were examined six months intervals at two different time points (T1 and T2). The bleeding episodes and Hemophilia Joint Health Score (HJHS) were recorded in all patients. The interobserver and intraobserver agreements on HEAD-US were assessed in six joints (elbow, knee, and ankle) of each hemophilic patient by different caregivers (radiologist and rheumatologist). Kappa (Kw) statistics (Kw >0.8-excellent, 0.61-0.80-good, 0.41-0.60-moderate, 0.21-0.40-fair and < 0.2 poor agreements) were used in SPSS 15.0 program.

Results: The number of joint bleedings in the right knee and ankle joints was significantly higher at the T2 than at the T1 (p < 0.05). The score of HJHS in the right ankle joint was significantly higher at T1 than at T2 (p < 0.05). Intraobserver agreement of radiologists was ranged from moderate (Kw=0.46) to good (Kw=0.75) for scoring synovitis, cartilage, and bone damages in 14 (78%) of 18 joints. Intraobserver agreement of rheumatologists was ranged from moderate (Kw=0.43) to excellent (Kw=0.84) for scoring synovitis, cartilage, and bone damages in 13 (72%) of 18 joints. Interobserver agreement between radiologists and rheumatologists at T1 was ranged from moderate (Kw=0.42) to good (Kw=0.78) for scoring synovitis, cartilage, and bone damages in 10 (56%) of 18 joints. Interobserver agreement between radiologists and rheumatologists at T2 was ranged from fair (Kw=0.38) to good (Kw=0.73) for scoring synovitis, cartilage, and bone damages in 10 (56%) of 18 joints.

Conclusion(s): Our study indicates that intraobserver agreement was better than interobserver agreement in the assessment of hemophilic arthropathy by HEAD-US.