PB0182 - Results of the implementation of home management in times of the covid-19 pandemic in patients with hemophilia A in Colombia

Sunday, July 10, 2022

6:30 PM – 7:30 PM

Location: Exhibition

Presentation Format: In-Person

Co-Author(s)

SS

Samuel Sarmiento, Sr.

Master in Epidemiologistic
Integral Solutions sd
Bogota, Distrito Capital de Bogota, Colombia

Presenting Author(s)

Gina Alejandra Diaz Mosquera, MD

Master of Public Health
Integral Solutions SD
Bogota, Distrito Capital de Bogota, Colombia

Co-Author(s)

Jc

Javier Mauricio cortes

pediatric onco hematology
Integral Solution SD
Bogota, Distrito Capital de Bogota, Colombia
CA

Carol Agudelo Rico

Master in Epidemiology
Integral Solutions Research
Bogota, Distrito Capital de Bogota, Colombia
JP

Jorge Enrique Peña Siado

pediatric onco hematology
Integral Solutions SD
Bogota, Distrito Capital de Bogota, Colombia
NR

Nelson Ramirez Plazas

pediatric onco hematology
Integral Solutions SD
Bogota, Distrito Capital de Bogota, Colombia
AP

Andres Parrado Rey

hematologist
Integral Solutions SD
Bogota, Distrito Capital de Bogota, Colombia
FM

Francisco Javier Meza Cadavid

hematologist
Integral Solutions SD
Bogota, Distrito Capital de Bogota, Colombia
CM

Cesar Alberto Montaño Mejía

pediatric onco hematology
Integral solutions SD
Bogota, Distrito Capital de Bogota, Colombia
AM

Alexi Maza Villadiego

onco-hematologist
Integral Solutions SD
Bogota, Distrito Capital de Bogota, Colombia
IP

Ivan Alfredo Perdomo Amar

hematologist
Integral solutions SD
Bogota, Distrito Capital de Bogota, Colombia

Background: On March 11, 2020, the World Health Organization declared COVID-19 a pandemic, generating impediments in the follow-up and treatment of patients with hemophilia, altering the provision of services.

Aims: To determine the number of bleeding episodes, hospitalizations and infection by COVID-19 after implementing a comprehensive management program adapted to the requirements of the pandemic in the framework of the provision of health services in patients with hemophilia A (HA).

Methods: Descriptive, retrospective study in a cohort of 107 patients with HA in a health center (Integral Solutions SD), between March-2020 and December-2021, based on the analysis of the variables: Annual bleeding rate (ABR), Hospitalization, cases by covid-19 in patients with HA in the face of the implementation of strategies such as: education, implementation of biosafety processes as well as facilitating treatment at the patients' homes within a comprehensive management program in times of pandemic.

Results: Of the 107 patients, 75.7% presented severe HA, all maintained their home prophylaxis, with an ABR of 0.52, of these bleeds, 99.1% had home management and 0.9% required hospitalization for one day. 1 patient confirmed by covid-19 and 5 with symptoms without diagnostic confirmation were reported, all recovered without needing hospitalization. Regarding immunization, 56.1% (n=60) were vaccinated, among whom the most frequent adverse event was pain where they received the vaccine (61.6%) followed by general malaise (25%).

Conclusion(s): During the COVID-19 pandemic, the personalized comprehensive management program in patients with HA, together with the implementation of home management and the preventive measures adopted, showed a trend in the reduction of ABR compared to national reports from previous years. On the other hand, the proportion of patients with Covid-19 infection or symptoms in the analyzed population was lower than the general population. All the patients who were vaccinated did not present adverse events different from the general population.