PB0709 - Bleeding Story of An Adolescent: Factor VII Deficiency And Repeat Iliopsoas Bleeding

Monday, July 11, 2022

6:30 PM – 7:30 PM

Location: Exhibition

Presentation Format: In-Person

Presenting Author(s)

Serap Karaman, MD

Prof Dr
Istanbul University, Istanbul School of Medicine, Division of Pediatric Hematology&Oncology
Istanbul, Istanbul, Turkey

Co-Author(s)

Aysegul Unuvar, MD

Prof. Dr.
Istanbul University, Istanbul School of Medicine, Division of Pediatric Hematolgy&Oncology
Istanbul, Istanbul, Turkey
SS

Sahin Sifa, MD

MD
Istanbul University Istanbul Medical Faculty, Pediatric Hematolgy-Oncology
Istanbul, Istanbul, Turkey
CE

Celal Caner Ercan

Dr,radiology department
Istanbul University Faculty of Medicine
ıstanbul, Istanbul, Turkey
gp

gökhan polat

Asc.Prof. Dr.Department of orthopedics and traumatology
Istanbul University Faculty of Medicine
ıstanbul, Istanbul, Turkey
MB

Mustafa Bilici

Fellow
Istanbul University, Istanbul School of Medicine, Division of Pediatric Hematology&Oncology
Istanbul, Istanbul, Turkey
DT

DENIZ TUGCU

Pof. Dr.
Istanbul University, Istanbul School of Medicine, Division of Pediatric Hematology&Oncology
Istanbul, Istanbul, Turkey
GT

Gülşah Tanyildiz

Assoc Prof
Istanbul University Istanbul Medical Faculty, Pediatric Hematolgy-Oncology
Istanbul, Istanbul, Turkey
ZK

Zeynep Karakas

Prof Dr
Istanbul University Istanbul Medical Faculty, Pediatric Hematolgy-Oncology
Istanbul, Istanbul, Turkey

Background: Factor VII deficiency is the most common of the rare factor deficiencies. The bleeding clinic is independent of the factor level and the level required for effective hemostasis varies from patient to patient.

Aims: It is aimed to draw attention to the importance of treatment compliance .

Methods: This case described to draw attention to rare bleeding disorders.

Results:

Case: A sixteen-year-old male patient; applied to the emergency department with the complaint of pain in the left groin. He had strained his leg and had pain while playing basketball 5 days before.He was examined for prolonged bleeding and recurrent nosebleeds after circumcision, and was diagnosed with factor VII deficiency (F VII level was between 27-53%). He was also under follow-up from rheumatology due to the diagnosis of FMF and was using colchicine and anakinra.
In the abdominal tomography, a 17 mm thick hematoma was observed in the left iliac fossa, near the ileopsoas muscle. The patient was started on rFVIIa (Novoseven) therapy. The patient, who received inpatient treatment for a total of 14 days, received 30 µgr/kg every six hours in the first two days, rFVIIa was administered every 12 hours between days 3-5. and once a day for the next 5 days. Novoseven was continued 3 days in a week. However, the patient applied to our outpatient clinic with pain in the left leg again one month later. In the USG performed after the factor was applied, it was observed that the hematoma, approximately 7 cm in size, recurred in the same place. The hematoma, regressed to 1 cm after 10 days. The patient, who was discharged, receives factor therapy three times a week and continues stretching exercises.

Conclusion(s): In the literature, no case of FVII deficiency with iliopsoas hemorrhage, who had a mild factor level as in our patient, was found.