PO0037 - Factor Infusion in Haemophilia in The Morning Increases Profilaxy Efficiency

Background: In patients who can use high doses of prophylactic factors, the moment of application may not be very important. However, in order to obtain an effective prophylaxis with a limited amount of factors, it is very important that the prophylaxis be administered just before active life.

Aims: Turkey is gradually improving hemophilia care. Most of our severe haemophilia patients use 4500 IU factor VIII or IX weekly as a prophylactic. Depending on body weight and bleeding frequency, the dose can be increased to 6000 IU weekly. This factor is paid by the social security institution for all patients. Our patients frequently infuse 1500 IU of factor 3 days a week. Patients who do the infusion or their family members cannot find time for the infusion due to the rush to get to work and school in the mornings. They mostly apply the infusion in the evening hours. For this reason, they are actively engaged in daily work during the hours when factor levels are the lowest. During the hours when the factor level is the highest, they are at rest or asleep.

Methods: In order to correct this situation, we planned a competition in order to apply prophylactic factor applications at the beginning of the day in the morning.

Results: In order to develop this habit, we, as the 19 May Haemophilia Association, organized a contest for our patients called "I make my factor in the morning, I start the day healthy". We asked our patients to take photos with own slogans while doing their prophylaxis infusions in the morning and share them with us on social media. Fifty-five of our patients participated in this campaign.

Conclusion(s): In patients receiving prophylaxis with a limited amount of factor, the application time in the morning maximizes the effectiveness.