RCSI
Prof. McElvaney (MB, FRCPI, FRCPC, DSc) is Professor of Medicine, Royal College of Surgeons in Ireland (RCSI) and the Director of the Irish Centre for Genetic Lung Disease. He has worked in the area of inflammatory lung disease over the past 30 years and has extensive experience in protease-anti-protease interactions in the lung and their effects on innate anti-microbial proteins. He has also significant experience in neutrophil biology and how inflammation affects neutrophil proteomics, metabolomics and degranulation pathways. He has published seminal papers on neutrophil/monocyte activation in AATD/COPD/CF along with significant research into the role of protease/anti-proteases, oxidants/anti-oxidants and ER stress in lung disease. He has performed the two largest trials to date on the risk for COPD in mild (MZ) and moderate (SZ) AATD and was lead investigator on the two biggest trials to date of augmentation therapy in people with severe (ZZ) AATD. More recently, he has evaluated the inflammatory manifestations of SARS-CoV-2 infection and how these might be ameliorated.
Saturday, November 5, 2022
3:30 PM – 5:30 PM ET