Stanford University
Jeffrey J. Wine, Ph.D. Benjamin Scott Crocker Professor of Human Biology, Emeritus, Stanford University, Stanford, CA United States
Until recently I direct the Cystic Fibrosis Research Laboratory at Stanford, which is devoted exclusively to understanding the pathophysiology of cystic fibrosis with the goal of ameliorating cystic fibrosis disease. Our laboratory developed methods for monitoring fluid secretion from individual submucosal glands, and was the first to demonstrate that airway glands, which produce antibiotic-rich mucus that helps protect the airways, display a profound secretory defect in cystic fibrosis. My current research seeks to expand these efforts toward attempts to understand the role of submucosal glands in protecting the airways from infections, and in particular how the loss of CFTR affects those functions. We see our work as complementing the work of many other investigators who are converging to exploit the great opportunities now available with CF mice, pigs, and ferrets.
Thursday, November 3, 2022
9:45 AM – 11:45 AM ET