Research Manager
University of Iowa
Ms. Yaling Yi is the Research Manager at the University of Iowa. She earned her master’s degree in animal physiology from Northwest Agriculture University in China in 2001 and started research on Cystic Fibrosis in 2006. She is one of the persons who generated the first CF ferret model in the world in 2007. Using the CF ferret model, her research has been focused on the role of CFTR in pancreas development, and the pathophysiological mechanisms of pancreatic diseases, with a particular focus on cystic fibrosis-related diabetes (CFRD) and pancreatitis. Her ongoing work focuses on elucidating mechanisms of how highly effective modulator therapy (HEMT) rescues abnormal glycemic control and CFRD pathogenesis.
She has published more than 66 scientific articles and abstracts, including being the first author of seminal papers titled Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets (Journal of Clinic Investment, 2012), A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling (Endocrinology, 2016), Abnormal Glucose Tolerance in Infants and Young Children with Cystic Fibrosis (Am J Respir Crit Care Med, 2016), Incretin dysfunction and hyperglycemia in cystic fibrosis: Role of acyl-ghrelin (Journal of Cystic Fibrosis, 2019), and Acute pancreatitis-induced islet dysfunction in ferrets (Pancreatology, 2021).