Department of Oncology, Children’s Research Center, University Children’s Hospital Zurich, Zurich, Switzerland
Zurich, Switzerland
Dr. Nazarian is the Head of DMG Research Center at University Children’s Hospital, Zurich Switzerland, and an Associate Professor of Pediatrics at the George Washington University and Children’s National Medical Center in Washington, D.C. In his role, Dr. Nazarian has formed national and international collaborations in an effort to establish a translational and multi-disciplinary team focusing on childhood high grade gliomas.
Dr. Nazarian’s research focus has been understanding the molecular pathways driving childhood brain cancers and, most importantly, finding ways for rapid translation of laboratory findings to the clinic. He has extensive expertise in forming and leading national and international collaborations, and in disease/pathway-focused team building. His research groups in Zurich and at Children’s National Medical Center in Washington DC, focus on developing biorepositories, disease preclinical models, performing molecular analyses, drug assays, and correlative studies for ongoing clinical trials. Working in close collaboration with Pacific Pediatric Neuro-Oncology Consortium (PNOC), Dr. Nazarian has established a working group encompassing 16 international institutions across North America, Europe and Australia. The primary goal of the team is to generate hypothesis derived preclinical data, test across institutions, validate using multiple preclinical DMG models, and provide input to the clinical team. The team’s goal is to accelerate the discovery of clinically translatable therapies for the treatment of childhood brain cancers.