NIMG-90 - Differentiation of intracranial solitary fibrous tumor and meningioma on conventional, diffusion-weighted, and dynamic susceptibility contrast perfusion MRI

Friday, November 18, 2022

7:30 PM – 9:30 PM ET

Location: West/Central Hall

Poster Presenter(s)

RK

Ryo Kurokawa, MD, PhD (he/him/his)

University of Michigan
Ann Arbor, United States

Author(s)

MK

Mariko Kurokawa, M.D.

University of Michigan
Ann arbor, United States
AB

Akira Baba, M.D., Ph.D.

University of Michigan
Ann arbor, United States
JK

John Kim, M.D., MRMD

University of Michigan
Ann arbor, United States
AC

Aristides Capizzano, M.D.

University of Michigan
Ann arbor, United States
JB

Jayapalli Bapuraj, MBBS

University of Michigan
Ann arbor, United States
AS

Ashok Srinivasan, M.D.

University of Michigan
Ann arbor, United States
TM

Toshio Moritani, M.D., Ph.D.

University of Michigan
Ann arbor, United States

Background and

Purpose: To evaluate the differences in the imaging findings of intracranial solitary fibrous tumor (SFT) and meningioma on dynamic susceptibility contrast (DSC) perfusion MRI, apparent diffusion coefficient (ADC), and conventional sequences.

Methods: Between January 2016 and April 2022, the study enrolled 14 (median, 46 years [range, 25–74]; six females; seven with DSC-MRI) and 27 patients (median, 53 years [21–83]; 23 females; all with DSC-MRI) with pathologically proven SFT and meningioma, respectively. The normalized relative cerebral blood volume and flow (nrCBV and nrCBF), percentage signal recovery (PSR), normalized mean ADC (nADCmean), and conventional imaging features, including T1-weighted hyperintensity, were evaluated and statistically compared using Bonferonni correction.

Results: PSR was significantly lower in SFT compared with that in meningioma (median, 22.5 [range, 6.4–48.8] vs. 70.1 [range, 18.6–104.2], p< 0.001). The majority of SFT showed mainly T1-weighted hyperintensities compared to the gray matter, while only one meningioma showed the finding (8/14 [57.1%] vs. 1/27 [3.7%], p< 0.001). No significant difference was observed in nrCBV, nrCBF, or nADCmean.

Conclusions: PFS was significantly lower in intracranial SFT compared with that in meningioma, indicating the difference in capillary permeability between the tumors. Comparing the hyperintensity on T1WI of the solid components with that of the cerebral cortex was a simple and useful characteristic to differentiate SFT from meningioma.