Baylor College of Medicine
Houston, United States
Kyle Eagen, Ph.D. is an Assistant Professor and CPRIT Scholar in Cancer Research at Baylor College of Medicine. He received his B.S. degree in Biological Sciences with a concentration in Biochemistry from Cornell University where he investigated the rapid chemical kinetics of neurotransmitter receptors in the laboratory of Dr. George Hess. He obtained his Ph.D. in Biophysics from Stanford University where he worked with Dr. Roger Kornberg studying chromatin and chromosome structure. After completing graduate training, Dr. Eagen began his independent career in 2017 as the inaugural Feinberg Fellow at the Northwestern University Feinberg School of Medicine within the Department of Biochemistry and Molecular Genetics. In 2021, he joined Baylor College of Medicine as an Assistant Professor in the Department of Molecular and Cellular Biology. He is a recipient of a 2017 NIH Director's Early Independence Award and was named a CPRIT Scholar in Cancer Research in 2021. The Eagen Lab combines concepts and approaches from biochemistry with methods and analytical tools from cell biology, molecular biology, pharmacology, genomics, and computational biology to determine how the three-dimensional structure of chromosomes regulates gene expression. His laboratory has revealed fundamental principles of how the spatial segregation of chromatin into distinct regions, or compartments, of the nucleus imparts biological function and how this compartmentalization goes awry in disease. His long-term goal is to develop pharmacological intervention of aberrant chromatin structure as a novel therapeutic approach for disease treatment.