VP Application Applied Cells Inc., California, United States
Tumor biology, immunology, and immune-oncology from multi-omics at single cell level has witnessed unprecedented acceleration in recent years, with a major contribution of such speedup from new technologies and products bursting into market. New technological solutions also contributed deterministically to the promise of cell-based therapy. However, standard sample preparation protocols widely practiced to obtain single cell suspension still involves decades-old centrifugation processes which are tedious and greatly affected by human factor. In development of cell therapy drugs, robust cell manufacturing systems that are flexible, adaptable to various processes, and involving minimal human factor, are widely sought after.
MARS Cell Separation Platforms incorporate innovations in multiple cell separation technologies. MARS are constructed as modular platforms to support wide range of applications in life science arena, including single cell analysis, precision medicine, as well as cell therapy. In this talk, we will present to you -
1) Case studies of using MARS high speed tunable acoustic chip technologies to purify single cells and sing cell nuclei from solid tissue dissociation cell suspension and demonstrate the reagent-free timesaving process on MARS compared to the conventional method.
2) Examples of MARS “add-add-run” magnetic cell separation solutions, reagents, and protocols, which allow both positive and negative selection of target cells from whole blood, apheresis product and bone marrows.
3) Closed fluidic systems which are designed to run large scale cell separation, in both magnetic cell separation and acoustic cells separation, to support cell therapy development.
We will show you how automated MARS cell separation platforms married the benefits of acoustic and magnetic cells separations in realizing first-of-its-kind cell separation results, and offering a simple, effective, and revolutionary solution to prepare cell samples for downstream applications.
