Mass photometry is a novel bioanalytical technology that provides insights into the mass distribution of biomolecules in their native state within minutes without the need for labelling, surface immobilization or big sample quantities. Its ease of use and single-molecule resolution make mass photometry the perfect tool for rapid assessments of sample purity, binding affinities or structural integrity across biomolecules ranging from differently sized proteins to DNA and even small viruses, such as AAVs. In this talk we will show how mass photometry can answer different biological questions and introduce a new mass photometry product that enables the automated mass characterisation of biomolecules in solution and increases measurement reproducibility, with low sample consumption.
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