Manager of BioA Applications Sartorius BioAnalytics Inc Carver, MN, United States
Abstract: Traditional methods for analyzing the kinetics of biomolecular interactions such as ELISA are often cumbersome and may require rigorous sample preparation. In addition, ELISA may not provide the information required for the confident understanding of a drug molecule’s mechanism of action (MOA). In contrast, the 96-well sample plate based Octet® family of instruments such as the Octet® R8 system provide researchers with an easy to use real time label-free system that can detect the interactions of a diverse range of biomolecules; from small molecules to proteins to viruses. The Octet® BLI platform offers an advanced fluidics-free approach with a wide variety of off-the-shelf Dip and Read Biosensors for rapid binding kinetics and quantitation analysis, enabling direct detections of not only purified biomolecules, but even those in complex media such as cell culture supernatants and lysates. The 96-channel Octet® RH96 system performs quantitation of 96 samples in as little as 2 minutes, and kinetic screening of 384 samples in 15 minutes. Analysis can be done using a single channel or up to 96 channels, enabling more flexibility in sample throughput when needs change. In addition, the Octet® BLI systems have been developed to operate reliably in a regulated environment. Sartorius offers Octet® 21 CFR Part 11 Software and a full line of GxP products and services as part of the GxP Package. In this poster, we demonstrate the performance of the BLI technology, applications in protein-protein and protein-small molecules interactions.
Scan and Win! Complete as many scavenger hunt questions as possible. You will find scavenger hunt QR Codes to scan on participating posters. Each participating poster in the exhibit hall will have a QR code next to it. For virtual participants, look for the scavenger hunt icon for participating posters.
SLAS Events
Instructions
Each poster participating in the scavenger hunt will have a SCAVENGER HUNT QR code. When that QR code is scanned using the SLAS2022 app, question about the poster will appear. You must answer the question correctly to collect points. BE SURE TO EXPLORE THE POSTER BEFORE SCANNING THE CODE! SLAS will award three prizes to the participants with the most points.
1st Prize - Comp Reg + Hotel/Airfare to SLAS2023 in San Diego
2nd Prize - $50 Starbucks Gift Card
3Rd Prize - $25 AMEX Gift Card
Keep an eye on the leader boards to see who’s at the TOP. Winners will be announced after SLAS2022.
Each participating poster in the exhibit hall will have a QR code next to it. For virtual participants, look for the scavenger hunt icon for participating posters.
