Practice Innovations
In the last 18 months we evaluated more than 70 patients with chronic skin lesions of different aetiology, infectious or not, with or without necrotic tissues, many of them not responding to the common treatments (both traditional and advanced dressings) for more than 6 weeks. We treated all the wounds with different medications (spray, cream, gauzes, alginate and hydrogel) containing Ozoile®, a pool of stable ozonides derived from olive oil*. We evaluated Infection Signs Disappearance (ISD) if present (according with Cutting & Harding Criteria), Debridement Time (DT) in case of necrotic wounds, Healing Rate (HR) and Healing Time (HT).
Results: All wounds achieved the complete healing within 100 days: 50% within 60 days. The mean ISD was 10.4 days; the mean DT was 15.6 days; the mean HR was 0.118 cm/week; the mean HT was 63.7 days. No wounds needed surgical procedures. No allergies, no adverse reactions, no induced pain.
Discussion: Ozoile® showed to be significantly effective in the treatment of chronic ulcers, regardless of the etiology of the lesions. The antiseptic activity is strongly effective against any kind of bacteria and fungi. The medication doesn’t induce pain and promotes granulating tissue and epithelialization also in hard-to-heal wounds from the first days of treatment. The use of Ozoile® can allow an interesting cost-saving due to the reduced times of infection removing, debridement ad healing.
Trademarked Items: *Rigenoma - Erbagil, Telese Terme (BN) - Italy
References: 1. Cutting K, Harding K. Cutting KF, White RJ, Mahoney P, Harding KG. Clinical identification of wound infection: a Delphi approach. EWMA Position Document, 2005.
2. Cassino R, Mignozzi C, Fiato F. Ozoile: an added value for a quicker bedsores healing. EPUAP (European Pressure Ulcer Advisory Panel) 21st Annual Meeting, 2019. Lyon (France)
3. Travagli V, Zanardi I, Valachi G, Bocci V. Ozone and ozonated oils in skin diseases: a review. Mediators of inflammation, Volume 2010 (2010), Article ID 610418