Clinical Research

(CR-007) Managament of Chronic venous insufficiency with a new dual compression system ; Results of a real life study in 702 patients

Co-Author(s):

Introduction: Compression therapy is the cornerstone of the management of patients presenting chronic venous insufficiency (CVI) from C3 to C6 stages of the CEAP Classification, as first line option in the acute decongestion phase of oedema and for the treatment of active venous leg ulcer (VLU). This study aimed to evaluate the efficacy and safety of a dual compression system in in outpatients with CVI problems under real-life conditions. Methods: A prospective, multicentre, observational study with a dual compression system (UrgoK2, Laboratoires Urgo, France) was performed in 103 centres in Germany. Main outcomes included wound healing rate, wound healing progression, assessment of oedema and acceptance of this compression therapy. Results: 702 VLU and/or with CVI oedema were treated with the dual compression system (DCS) 27±17 days. Bandages were changed 1–2 times a week in 51.7%, 3–4 times a week in 448 (28.7%), >4 times a week in 306 (19.6%) of visits. By last visit, 30.9% VLUs healed and percentage of patients with oedema (with or without leg ulcer) decreased from 74.1% to 24.6%. Improvement of ankle mobility was reported in 44.2%. Patient tolerance and physician acceptance was positive for approx. 95% of the patients, regardless of the treated condition, VLU and/or limb oedema. Bandage slippage reported in < 4 patients Discussion: Real-life data documented in this large observational study of non-selected patients receiving compression therapy in daily practice confirm the benefits and safety profile of the evaluated compression system previously reported in various clinical trials. This compression system can be considered as a first line intervention untill healing in VLUs and leads to reduce the oedema caused by CVI. Trademarked Items: UrgoK2 Compression Bandage References: 1. Benigni JP, Lazareth I, Parpex P, Gerard JL, Alves M, Vin F, Meaume S, Senet P, Allaert FA. Efficacy, safety and acceptability of a new two-layer bandage system for venous leg ulcers. J Wound Care. 2007 Oct;16(9):385-90. doi: 10.12968/jowc.2007.16.9.27866. https://pubmed.ncbi.nlm.nih.gov/17987751/
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