Case Series/Study

(CS-130) The Use of Fragmented Intact Fish Skin* in Patients Promoting Closure in Difficult to Heal Wounds in Cancer Patients

Co-Author(s):

Introduction: Surgical wounds in patients who have been treated with chemotherapy and radiation are notoriously difficult to heal primarily and even more difficult to heal with secondary intention.

Methods: In this clinical case study, we present with one TNBC 69-year- old female patient with a non healing wound due to radiation in a heavily pretreated patient with chemotherapy and targeted therapy. She was treated with debridement and wound vac prior to placement of fragmented FSG. The FSG was prepared based on the manufacturer’s instructions. Only simple secondary dressings were needed to secure the graft. We placed the FSG at weekly intervals for 4 weeks.

Results:

Once granulation tissue was evident then FSG was applied with excellent epithelialization In a wound that was not expected to heal, it has healed with secondary intention.

Discussion:

69 y female with TNBC locally advanced with bilateral breast cancer. In the area of the left sternal border, the residual malignancy had eroded to the bone. She had refused chest wall resection. Attempt at local resection left residual disease and positive margins. She underwent radiation and continued chemotherapy. Her first presentation to the Wound center, showed breakdown of the left medial edge of the sternum in radiated tissue. Biopsy showed no evidence of malignancy. Wound care was initiated with Wound Vac followed by puraply/Wound VAc. Once granulation tissue was evident then FSG was applied with excellent epithelialization In a wound that was not expected to heal, it has healed with secondary intention.

Trademarked Items: *KerecisTM, Kerecis, Isafjordur, Iceland

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