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Poster Schedule
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Mon, Oct 17
Tue, Oct 18
Wed, Oct 19
Poster Schedule
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Tuesday, October 18, 2022
9:30 AM – 10:30 AM
ET
(T0930-01-01) Enhanced Conjugated Linoleic Acid Paclitaxel-Loaded Superparamagnetic Iron Oxide Nanoparticles for Anti-proliferative Activity in Non-Small-Cell Lung Carcinoma
Favorite
9:30 AM – 10:30 AM
ET
(T0930-01-02) A Physical Picture for the Dissolution Process of Copovidone ASDs
Favorite
9:30 AM – 10:30 AM
ET
(T0930-01-04) Sublimation Loss of Drugs from Topical Products at the Site of Application
Favorite
9:30 AM – 10:30 AM
ET
(T0930-02-08) Alteration of Drug Metabolizing Enzyme and Transporter Expression Mediated by Electronic Cigarette Exposure: Implication in Drug Interaction
Favorite
9:30 AM – 10:30 AM
ET
(T0930-02-09) Short-Term Administration with Immunosuppressants Suppresses Preclinical Immunogenicity against a Human Monoclonal Antibody in Rats
Favorite
9:30 AM – 10:30 AM
ET
(T0930-02-10) A Mechanistic Ocular PK/PD Model with Systemic Target-Mediated Drug Disposition to Predict Human PK for Intravitreally Administered Anti-Tie2 Agonist
Favorite
9:30 AM – 10:30 AM
ET
(T0930-02-11) Toxicokinetics of GA200, an Inhibitor of AMPK Ubiquitination via Blockade of E3-Ligase, following Daily Oral Administration in Rats and Monkeys
Favorite
9:30 AM – 10:30 AM
ET
(T0930-03-13) Preparation and Evaluation of 3D Printed Capsaicin-Loaded Rod-Shaped Implants for Treating Obesity and Hyperlipidemia
Favorite
9:30 AM – 10:30 AM
ET
(T0930-03-14) Role of Excipients on Drug Release from Long-Acting Intrauterine Systems
Favorite
9:30 AM – 10:30 AM
ET
(T0930-03-15) How to Ensure a Successful Tablet Coating Formulation Development by Using Polyvinyl Alcohol in Combination with Calcium Carbonate to Provide an Alternative to Titanium Dioxide
Favorite
9:30 AM – 10:30 AM
ET
(T0930-03-16) Investigating the Synergistic Effect of Polymethacrylates and HPC as Polymeric Carrier for Drug Solubility Enhancement
Favorite
9:30 AM – 10:30 AM
ET
(T0930-03-17) Controlled Delivery of Emtricitabine and Bictegravir from Nanoparticles for the Management of HIV Associated Neurocognitive Disorders (HAND): Effect of Methods of Preparation and Surfactants
Favorite
9:30 AM – 10:30 AM
ET
(T0930-04-20) Hansen Solubility Parameters Estimates of Amorphous Dispersion Behavior Are Accurate in Some Cases but Often Inconclusive
Favorite
9:30 AM – 10:30 AM
ET
(T0930-04-21) Role of Drug–Polymer Interactions and Polymer Concentration on Critical Cooling Rate during Hot-Melt Extrusion of Amorphous Solid Dispersions
Favorite
9:30 AM – 10:30 AM
ET
(T0930-04-22) Evaluating Immunization Efficacy of Self-administrable Subunit Microparticulate COVID-19 Vaccine Delivered by Nasal, Buccal, and Dermal Routes
Favorite
9:30 AM – 10:30 AM
ET
(T0930-04-23) Put a Ring on It: 2-Hydroxypropyl-β-cyclodextrin-Complex-Cabotegravir Sodium with Hydrogel-Forming Microarray Patches for Minimally Invasive HIV- Pre-exposure Prophylaxis
Favorite
9:30 AM – 10:30 AM
ET
(T0930-05-25) Understanding the Efficacy of Gemcitabine and Paclitaxel on Desmoplastic Pancreatic Cancer Spheroids
Favorite
9:30 AM – 10:30 AM
ET
(T0930-05-27) Viral Mimicry NanoVaccine Boosting B Immunity to Enhance Anti-cancer Efficacy
Favorite
9:30 AM – 10:30 AM
ET
(T0930-05-28) Antipsychotic Agent Pimavanserin, a Potential Therapy for Glioblastoma
Favorite
9:30 AM – 10:30 AM
ET
(T0930-05-29) Effect of Propofol on the In Vitro Model of the Blood-Brain Barrier Based on Induced Pluripotent Stem Cell-Derived Human Brain Microvascular Endothelial Cells
Favorite
9:30 AM – 10:30 AM
ET
(T0930-06-31) Assessing the Analytical Similarity of the Biosimilar Candidate ABP 654 to Ustekinumab Reference Product
Favorite
9:30 AM – 10:30 AM
ET
(T0930-06-32) Assessing Key Attributes of Adeno-Associated Viral Proteins Using HPLC-FLD-Intact Accurate Mass Analysis
Favorite
9:30 AM – 10:30 AM
ET
(T0930-06-33) Impact of Apparatus and Adaptor Setups on In Vitro Drug Release of Ophthalmic Semi-solid Drug Products
Favorite
9:30 AM – 10:30 AM
ET
(T0930-06-34) 3D DLP Printed Cannabinoid Microneedles Patch and Its Pharmacokinetic Evaluation in Sprague Dawley Rats
Favorite
9:30 AM – 10:30 AM
ET
(T0930-06-35) Automated Adaptive Perfusion: A Novel In Vitro Drug Release Testing System for Complex Drug Products
Favorite
9:30 AM – 10:30 AM
ET
(T0930-07-38) Dissolution Bioequivalence Safe Space Assessment of Molnupiravir and NHC Using Physiologically Based Biopharmaceutics Modeling
Favorite
9:30 AM – 10:30 AM
ET
(T0930-07-39) Developing an In Vitro System to Emulate the In Vivo Subcutaneous Environment and Predict the Fate of Drugs in Subcutaneous Delivery: Assessment of Small Molecule Drugs
Favorite
9:30 AM – 10:30 AM
ET
(T0930-07-40) Tunable Drug Release from Fused Deposition Modelling (FDM) 3D Printed Tablets Fabricated Using a Novel Extrudable Polymer
Favorite
9:30 AM – 10:30 AM
ET
(T0930-07-41) Development of Scalable and Inhaled Nintedanib-Loaded Polymeric Nanoparticles for Localized Therapy of Idiopathic Pulmonary Fibrosis
Favorite
9:30 AM – 10:30 AM
ET
(T0930-08-43) Enhancing the “Right First Time” Concept in Continuous Manufacturing–Development Strategy
Favorite
9:30 AM – 10:30 AM
ET
(T0930-08-44) LC-PDA and a Multivariate Curve Resolution – Alternating Least Square Algorithm for Identification and Quantification of Co-eluting Impurities in Pharmaceutical Analysis
Favorite
9:30 AM – 10:30 AM
ET
(T0930-08-45) Effect of Die Taper and Precompression on Air Entrapment during Tablet Compression
Favorite
9:30 AM – 10:30 AM
ET
(T0930-08-47) Effect of Critical Material Attributes of Low-Substituted Hydroxypropyl Cellulose (L-HPC) on Twin Screw Wet Granulation of Acetaminophen
Favorite
9:30 AM – 10:30 AM
ET
(T0930-09-49) Validation of Ultra-High Sensitive SIMOA Assays for the Quantitation of Neurofilament Light Chain (NF-L) and Glial Fibrillary Acidic Protein (GFAP)
Favorite
9:30 AM – 10:30 AM
ET
(T0930-09-50) Evaluation of the Tasso-M20 Microsampling in Support of Clinical PK Studies
Favorite
9:30 AM – 10:30 AM
ET
(T0930-09-51) Novel Pharmacokinetic and Hematological Monitoring Methods Validated for Small Volume Blood Sampling for Gene or Cell Therapies
Favorite
9:30 AM – 10:30 AM
ET
(T0930-09-53) Development and Validation of a Human Soluble MICA Biomarker Assay for use in Clinical Studies
Favorite
9:30 AM – 10:30 AM
ET
(T0930-09-54) A Generic Approach to Monkey Anti-drug Antibodies Assay Development for Antibody Therapeutic Preclinical Studies
Favorite
9:30 AM – 10:30 AM
ET
(T0930-10-55) Differential Gene Expression of Human Brain Endothelial Cells Compared to Endothelial Cells Co-cultured with Pericytes
Favorite
9:30 AM – 10:30 AM
ET
(T0930-10-56) An End-to-End Method for AI-Driven Peptide Vaccine Formulation and Translation through Deep Learned Exosome Precision Drug Delivery
Favorite
9:30 AM – 10:30 AM
ET
(T0930-10-57) Pharmacokinetic-Pharmacodynamic Modeling of the Antinociceptive Effect of Mitragynine, the Most Abundant Kratom Alkaloid in Mice
Favorite
9:30 AM – 10:30 AM
ET
(T0930-10-58) Hazard Analysis of Amorphous Silica Nanoparticle via Acquired Immune System
Favorite
9:30 AM – 10:30 AM
ET
(T0930-10-59) Interventional Treatment with an mPGES-1 Inhibitor Halts Further Growth of Abdominal Aortic Aneurysms in the Ang-II Mouse Model
Favorite
9:30 AM – 10:30 AM
ET
(T0930-11-61) Cannabinoids Selectively Alter Cytochrome P450(CYP) Activity in Primary Cultures of Human Hepatocytes
Favorite
9:30 AM – 10:30 AM
ET
(T0930-11-62) Exploration of Predictive Bioequivalence: Comparison of Methods to Incorporate In Vitro Dissolution Data in Pharmacokinetic Modeling of BCS Class II Acidic Drugs
Favorite
9:30 AM – 10:30 AM
ET
(T0930-11-64) Cost-Effective Strategy - An Innovative Approach Assessing the Drifting Bioavailability of Fixed-Dose Combination Formulations
Favorite
9:30 AM – 10:30 AM
ET
(T0930-11-65) Metformin Treatment or Cotreatment with Statins Pharmacokinetics and Pharmacodynamics on Diabetes Patients Before or Post Gastric Bypass Surgery
Favorite
9:30 AM – 10:30 AM
ET
(T0930-12-67) Glimepiride Releases from Laboratory Compounded and Two Commercial Tablets Using a Proposed Three Stage In Vitro Dissolution Study
Favorite
9:30 AM – 10:30 AM
ET
(T0930-12-68) Eudragit Coated Polymeric Microneedles for Intradermal Controlled Delivery of Drugs
Favorite
9:30 AM – 10:30 AM
ET
(T0930-12-69) A Single Local Delivery of Paclitaxel and Nucleic Acids via an Immunoactive Polymer for Cancer Immunotherapy
Favorite
9:30 AM – 10:30 AM
ET
(T0930-12-70) Imidazolium-Based Ionic Liquids in Orally Dissolving Films (ODFs) for Delivering Antihistamines
Favorite
9:30 AM – 10:30 AM
ET
(T0930-12-71) Preparation and Characterization of Apixaban with Anti-crystallizer PLGA Microsphere Using Prilling by Vibrating Microfluidic Device
Favorite
9:30 AM – 10:30 AM
ET
(T0930-12-72) Preparation and In Vivo Evaluation of Sustained Release Docetaxel-Loaded Lipid Nanoparticles Using Hot Nanoemulsion-Based Technique
Favorite
10:30 AM – 11:30 AM
ET
(T1030-01-02) N-nitrosodimethylamine and Dissolution Assessment of Commercial Metformin Products in In-Use Stability Testing
Favorite
10:30 AM – 11:30 AM
ET
(T1030-01-03) Development and Characterization of Multi-layer Self-Nanoemulsifying Pellets Using Fluid Bed Coating Technique to Enhance the Dissolution and Stability of Ramipril
Favorite
10:30 AM – 11:30 AM
ET
(T1030-01-04) Microparticles-Loaded Dissolving Microarray Patches for the Depot Intradermal Long-Acting Delivery of Atorvastatin
Favorite
10:30 AM – 11:30 AM
ET
(T1030-03-13) Design and Optimization of Ciprofloxacin Hydrochloride Biodegradable 3D Printed Ocular Inserts: Full Factorial Design In Vitro and Ex Vivo Evaluations
Favorite
10:30 AM – 11:30 AM
ET
(T1030-03-14) Investigation of Phenoxyethanol Permeation Using the Skin Parallel Artificial Membrane Permeability Assay (PAMPA) Membrane and Mammalian Skin: Correlation and Rank Order
Favorite
10:30 AM – 11:30 AM
ET
(T1030-03-16) Research of Powder Properties of Microcrystalline Cellulose Grades Desirable for Direct Continuous Compression System
Favorite
10:30 AM – 11:30 AM
ET
(T1030-03-18) Drug and Colloidal Characteristics Impact the Unstirred Water Layer Thickness
Favorite
10:30 AM – 11:30 AM
ET
(T1030-04-19) Formulation Development of Dietary Supplements and Stability Prediction Using Accelerated Stability Assessment Program
Favorite
10:30 AM – 11:30 AM
ET
(T1030-04-21) Lyotropic Liquid Crystal Drug Delivery System: Cubosome Encapsulate Cromolyn Sodium for Oral Delivery
Favorite
10:30 AM – 11:30 AM
ET
(T1030-04-22) Codelivery of Hydrophobic and Hydrophilic Drugs with PLGA-Tipped Hydrogel-Forming Hybrid Microneedle Patches
Favorite
10:30 AM – 11:30 AM
ET
(T1030-05-26) Immortalization and Functional Screening of Human Antibody Repertoires from Chronic HIV-1 Infected Patients
Favorite
10:30 AM – 11:30 AM
ET
(T1030-05-27) Dendrimer Conjugated nSMase2 Inhibitor (D-DPTIP) as a Novel Treatment for Alzheimer’s Disease
Favorite
10:30 AM – 11:30 AM
ET
(T1030-05-28) Sex Difference of Glucose Transport in an Alzheimer’s disease Transgenic Mouse Model
Favorite
10:30 AM – 11:30 AM
ET
(T1030-05-29) Radioprotective Effects of a Standardized Tocotrienol Rich Extract from Annato Seeds (
Bixa orellana
L.)
Favorite
10:30 AM – 11:30 AM
ET
(T1030-06-31) Strategies for Correcting Peak Fronting of Oxycodone Hydrochloride, Naloxone Hydrochloride and Related Substances Observed in Reversed—Phase Liquid Chromatography
Favorite
10:30 AM – 11:30 AM
ET
(T1030-06-32) Characterization and Quantification Analysis of Onivyde Irinotecan Liposome Injection
Favorite
10:30 AM – 11:30 AM
ET
(T1030-06-33) Real World Application of Deterministic, Non-destructive CCI Testing on the Entire Batch (100%) - Not a Concept Anymore!
Favorite
10:30 AM – 11:30 AM
ET
(T1030-06-34) Improving Patient Understanding of Prescription Medications Using Science Communication Strategies
Favorite
10:30 AM – 11:30 AM
ET
(T1030-06-35) A Systematic In Vitro Study to Evaluate Age-Appropriate Oral Administration Routes for Clinical Pediatric Delivery of an Oral Granules Formulation
Favorite
10:30 AM – 11:30 AM
ET
(T1030-07-38) Nanovesicle Delivery Systems Containing Doxorubicin Hydrochloride and Paclitaxel for Breast Cancer Treatment
Favorite
10:30 AM – 11:30 AM
ET
(T1030-07-39) Development, Characterization and Stability Studies of Amphotericin B and Nonadecanoic Acid loaded Nanostructured Lipid Carriers for Fungal Keratitis
Favorite
10:30 AM – 11:30 AM
ET
(T1030-07-40) Delivering Smarter Medicines with On-Dose Microtaggants and Smartphone Technology
Favorite
10:30 AM – 11:30 AM
ET
(T1030-07-41) Understanding the Role of Phase Separation in Dissolution of Amorphous Solid Dispersions (ASDs)
Favorite
10:30 AM – 11:30 AM
ET
(T1030-07-42) Fabrication of Controlled Release Dosages via Selective Laser Sintering Three-Dimensional (3D) Printing Technology
Favorite
10:30 AM – 11:30 AM
ET
(T1030-08-43) An Efficient HEK293 Cell Line for Scalable, GMP-Ready Production of Adeno-Associated Viral Vectors
Favorite
10:30 AM – 11:30 AM
ET
(T1030-08-44) Effect of Coating of Andersen Cascade Impactor and Next Generation Impactor on the Aerodynamic Particle Size Distribution of Nine Commercial Metered Dose Inhalers
Favorite
10:30 AM – 11:30 AM
ET
(T1030-08-45) Tribological Response of Hydroxyethyl Cellulose Gels as a Function of Isopropyl Alcohol Concentration and Angular Velocity Profile
Favorite
10:30 AM – 11:30 AM
ET
(T1030-08-46) Factors to Consider for Increasing HPLC Column Lifetime
Favorite
10:30 AM – 11:30 AM
ET
(T1030-08-47) Characterization and Optimization of the Powder Flow Investigated with Different Feed Frame Setups Used for Continuous Manufacturing
Favorite
10:30 AM – 11:30 AM
ET
(T1030-08-48) A Search for Novel, Crystalline Nicotine Salts and Cocrystals
Favorite
10:30 AM – 11:30 AM
ET
(T1030-12-67) Multiphysics Simulations and Pharmacokinetic Modeling of Long-Acting Injectable Delivery Systems
Favorite
10:30 AM – 11:30 AM
ET
(T1030-12-68) Applications of Deep Learning to Predict Aerosol Performance of Dry Powders for Inhalation
Favorite
10:30 AM – 11:30 AM
ET
(T1030-12-69) Development of Amorphous Solid Dispersion of Aprepitant Using Sucrose Acetate iso butyrate for Dissolution and Bioavailability Enhancement
Favorite
10:30 AM – 11:30 AM
ET
(T1030-12-70) CSTD Force Testing Informs on Stopper Intrusion and the Force Users Must Overcome
Favorite
10:30 AM – 11:30 AM
ET
(T1030-12-71) Enhancing Nucleic Acid Delivery to the Alcoholic Liver Using Polarized Macrophage-Derived Biomimetic Nanoparticles
Favorite
10:30 AM – 11:30 AM
ET
(T1030-12-72) Pharmaceutical Formulation and In Vitro Analyses of a Paediatric Fixed-Dose Combination Antimycobacterial Reconstitutable Oral Suspension
Favorite
10:30 AM – 11:30 AM
ET
(T1030-04-24) Intracellular Delivery of Plasmid DNA Using TPGS Formulated Lipid Nanoparticles
Favorite
11:30 AM – 12:30 AM
ET
(T1130-01-02) In Vitro Digestion-Diffusion Model for Predicting In Vivo Performance of Lipid-Based Formulations
Favorite
11:30 AM – 12:30 PM
ET
(T1130-01-04) Expandable Single-Component Gastroretention Devices: Shape Optimization and Proof of Concept for Extended Gastric Residency and Drug Release In Vivo
Favorite
11:30 AM – 12:30 PM
ET
(T1130-01-05) Recent Advances in ASD Formulations: HIPROS and Dispersome
Favorite
11:30 AM – 12:30 PM
ET
(T1130-01-06) Eliminating Upper Gastrointestinal Irritation of a Novel Therapeutic (SCTL-007) by Developing Modified Release Matrix Tablets Utilizing HPMC Polymers
Favorite
11:30 AM – 12:30 PM
ET
(T1130-02-07) Revealing More of the Bioactive Phospholipidome in Plasma Using the High Performance Surface LC/MS/MS
Favorite
11:30 AM – 12:30 PM
ET
(T1130-02-08) In Vitro Lymphatic Absorption Screening with Primary Human Small Intestinal Cells
Favorite
11:30 AM – 12:30 PM
ET
(T1130-02-09) Effect of In Situ Immunization with Vidutolimod in an Oral Leukoplakia Model
Favorite
11:30 AM – 12:30 PM
ET
(T1130-02-10) Positively Charged Surface in LIGHT Trimers Fused with Fc, a Ligand for Lymphotoxin-b Receptor (LTbR) and HVEM, Caused a Non-specific Interaction with Cells Leading to Fast Systemic Clearance in Mice
Favorite
11:30 AM – 12:30 PM
ET
(T1130-02-11) A Generic Method Approach to Nonclinical Anti-Drug Antibody Assessment
Favorite
11:30 AM – 12:30 PM
ET
(T1130-03-13) Mechanical Properties of Reinforced Polyvinyl Alcohol Cryogels
Favorite
11:30 AM – 12:30 PM
ET
(T1130-03-15) Development and In Vitro Characterization of STAT6 siRNA Loaded PEGylated Gelatin Nanocarriers as an Anti-Asthmatic Therapy
Favorite
11:30 AM – 12:30 PM
ET
(T1130-03-16) Thermodynamic Phase Diagrams for Predicting Drug-Polymer Miscibility of High Melting Point Drugs with Poly-2-ethyl-tetra-oxazoline for Development of Amorphous Solid Dispersions
Favorite
11:30 AM – 12:30 PM
ET
(T1130-03-17) Kinetic Barriers to Disproportionation of Salts of Weakly Basic Drugs
Favorite
11:30 AM – 12:30 PM
ET
(T1130-03-18) Impact of Coating Process Parameters on Drug Layering of Sitagliptin over Metformin HCl ER Tablets
Favorite
11:30 AM – 12:30 PM
ET
(T1130-04-19) A Novel Self-Crosslinked Matrix Microneedle Patch for “Smart” Delivery of Insulin at Hyperglycemia
Favorite
11:30 AM – 12:30 PM
ET
(T1130-04-20) An Improvement Grade of Hypromellose for Industrial Scale CR Tablet Manufacturing
Favorite
11:30 AM – 12:30 PM
ET
(T1130-04-22) Preparation and Evaluation of 2D Printing Controlled Release Film Containing Fine Dose Theophylline
Favorite
11:30 AM – 12:30 PM
ET
(T1130-04-23) Development of a Low-Dose Pilocarpine Ophthalmic Formulation that is Stable, Well-Tolerated and Bioavailable at a Near-Neutral pH for the Treatment of Presbyopia
Favorite
11:30 AM – 12:30 PM
ET
(T1130-04-24) A Potential Mechanism of Tabletability Flip Phenomenon
Favorite
11:30 AM – 12:30 PM
ET
(T1130-05-25) Interaction with Macrophages Alters the Susceptibility of Cancer Cells to Ferroptosis
Favorite
11:30 AM – 12:30 PM
ET
(T1130-05-26) Developing a Dual Prodrug for Triggered Antibiotic Activation
Favorite
11:30 AM – 12:30 PM
ET
(T1130-05-27) Development of a Delayed Release Softgel Dosage Form
Favorite
11:30 AM – 12:30 PM
ET
(T1130-05-28) The Inhibition of Proteolytic and ATPase Activities of the Proteasome by the BTK Inhibitor CGI-1746
Favorite
11:30 AM – 12:30 PM
ET
(T1130-05-29) Endogenous Blood-Brain Barrier Transporters are Critical Determinants of Neuroprotective Drug Efficacy in Ischemic Stroke
Favorite
11:30 AM – 12:30 PM
ET
(T1130-06-31) Stability of 0.9% Sodium Chloride IV Fluid Bags in the Prehospital Setting of Qatar: Protocol Development
Favorite
11:30 AM – 12:30 PM
ET
(T1130-06-32) Solid-State Stabilization of Proteins in Highly-Loaded Melt Extrudates – Characterization of Protein Integrity
Favorite
11:30 AM – 12:30 PM
ET
(T1130-06-33) Midazolam Buccal Films: Development and Characterization for Palliative Care
Favorite
11:30 AM – 12:30 PM
ET
(T1130-06-34) Impact of Formulation Processes on Dosage Form Determination of Phytonadione Injectables
Favorite
11:30 AM – 12:30 PM
ET
(T1130-06-35) Freeze-Dried-Microspheres: Low Density, Flowability and Processibility
Favorite
11:30 AM – 12:30 PM
ET
(T1130-07-37) Can an Excipient System including Magnesium Stearate Resist Mixing Times?
Favorite
11:30 AM – 12:30 PM
ET
(T1130-07-38) The Influence of the Chiral Coformer Tryptophan on the Physical Stability of Co-amorphous Systems with Indomethacin as Model Drug
Favorite
11:30 AM – 12:30 PM
ET
(T1130-07-40) Enhancement of Transdermal Permeation of Cannabinoids and Their Pharmacodynamic Evaluation in Rats
Favorite
11:30 AM – 12:30 PM
ET
(T1130-07-41) Cyclodextrin Enabled Formulations of Unstable and Poorly Soluble Compounds for Topical Ophthalmic Delivery
Favorite
11:30 AM – 12:30 PM
ET
(T1130-08-43) Peptide Mapping of Monoclonal Antibody (mAb) Using an Integrated Online Protein Digest LCMS Platform
Favorite
11:30 AM – 12:30 PM
ET
(T1130-08-44) Dexamethasone Intravitreal Implants: Manufacture, Characterization, and Elucidation of Drug Release Mechanisms
Favorite
11:30 AM – 12:30 PM
ET
(T1130-08-45) Automating Analytical Method Development with LabSolutions MD: Separating Cannabinoid Stereoisomers using Analytical Quality by Design (AQbD) Principles from ICH Q2(R2) and ICH Q14
Favorite
11:30 AM – 12:30 PM
ET
(T1130-08-46) Process Development of API in Continuous Manufacturing
Favorite
11:30 AM – 12:30 PM
ET
(T1130-08-47) Building Fundamental Understanding of Drug Release Mechanisms via Release of Functional Excipients
Favorite
11:30 AM – 12:30 PM
ET
(T1130-09-49) Bioanalytical Considerations in ANDAs with Analyte(s) as Endogenous Compounds Based on Commonly Observed Deficiencies
Favorite
11:30 AM – 12:30 PM
ET
(T1130-09-50) Effects of Brij
®
O20 as a Solubilizer and Stabilizer in Support of In Vitro Permeation Testing for Topical Dermatological Formulations
Favorite
11:30 AM – 12:30 PM
ET
(T1130-09-51) Circulating Tumor Cells as a Biomarker for Evaluating Tumor Progression and Treatment Response in Patients with Gastrointestinal Malignancies
Favorite
11:30 AM – 12:30 PM
ET
(T1130-09-52) Development of a Robust and Sensitive Microflow LC-MS/MS Workflow for the Analysis of Oligonucleotides
Favorite
11:30 AM – 12:30 PM
ET
(T1130-09-53) Sensitivity Improvement for the Quantitation of Antisense Oligonucleotides in Plasma Using Hybridization Microflow LC-MS/MS
Favorite
11:30 AM – 12:30 PM
ET
(T1130-10-55) The Mechanisms Governing the Positive Feedback Loop between Cerebrovascular Inflammation and Amyloid Beta Accumulation
Favorite
11:30 AM – 12:30 PM
ET
(T1130-10-57) Studying Protein Interactions Under Hydrodynamic Stress
Favorite
11:30 AM – 12:30 PM
ET
(T1130-10-58) Predictability of In Vitro Hepatocyte Induction Data in a PBPK Framework for CYP3A4 Induction Risk Assessment
Favorite
11:30 AM – 12:30 PM
ET
(T1130-10-59) Simultaneously Inactivating Three or all Four Penicillin-Binding Proteins (PBPs) among PBP1a, 1b, 2 and 3 Synergistically Kills
Acinetobacter baumannii (AB)
Favorite
11:30 AM – 12:30 PM
ET
(T1130-11-61) A Computational Semi-mechanistic Pharmacology Model of ATG101, a PD-L1/4-1BB Bispecific Antibody for Treatment of Solid Tumors
Favorite
11:30 AM – 12:30 PM
ET
(T1130-11-62) A Quantitative Systems Pharmacology (QSP) Model to Predict Kinetics of TCR-Engineered T Cell Therapies in Solid Tumors
Favorite
11:30 AM – 12:30 PM
ET
(T1130-11-63) Prediction of Rifampin Exposure Using a Single Concentration Point in Patients with Tuberculosis
Favorite
11:30 AM – 12:30 PM
ET
(T1130-11-64) Physiologically Based Pharmacokinetic Modelling to Predict the Pharmacokinetics of Aspirin and Its Metabolite Salicylic Acid after Intravenous, Oral, and Rectal Administration
Favorite
11:30 AM – 12:30 PM
ET
(T1130-11-65) Pharmacokinetics of LLP2A-Alendronate following Ascending Intravenous Dosing to Patients with Osteopenia Secondary to Glucocorticoids
Favorite
11:30 AM – 12:30 PM
ET
(T1130-12-68) Thermosensitive
Lactobacillus brevis
-Loaded Composite Double-Layered Dressing with Improved Mechanical Properties and Excellent Wound Recovery
Favorite
11:30 AM – 12:30 PM
ET
(T1130-12-69) Multifunctional Terpolymeric Blood-Brain Barrier Penetrating MnO
2
-Loaded Nanoparticles for Tumor Microenvironment Modulation and Radiation Sensitization of Glioblastoma
Favorite
11:30 AM – 12:30 PM
ET
(T1130-12-70) Development and Evaluation of Polyvinylpyrrolidone and Chitosan-Based Film Forming Gel containing Acyclovir
Favorite
11:30 AM – 12:30 PM
ET
(T1130-12-72) Structures of Glasses Created by Multiple Kinetic Arrests
Favorite
11:30 AM – 12:30 PM
ET
(T1130-07-42) Chiral Resolution by Crystallization: The Case of Arabitol
Favorite
12:30 PM – 1:30 PM
ET
(T1230-01-01) Developing a Stable Model Formulation to be Used as a Platform Technology for BCS Class II and IV Hydrophobic Molecules with Log P >3 while Using an Aprotic Solvent System as a Solubilizer and Carrier
Favorite
12:30 PM – 1:30 PM
ET
(T1230-01-02) Stabilization of Recombinant DNA in a Polymer Based Film Matrix
Favorite
12:30 PM – 1:30 PM
ET
(T1230-01-03) Identification of Critical Spray-Drying Process Parameters for Preparing Size Tunable Microparticles using Polyvinyl Pyrrolidone and Sodium Alginate
Favorite
12:30 PM – 1:30 PM
ET
(T1230-01-04) Enteric Coating of an Amorphous Solid Dispersion: An Emerging Strategy to Enhance the Dissolution Performance in Stimulated Gastrointestinal Fluids
Favorite
12:30 PM – 1:30 PM
ET
(T1230-01-05) Charcoal Drug Adsorption Efficiency in Various Solvents
Favorite
12:30 PM – 1:30 PM
ET
(T1230-03-13) Effect of α-tocopherol Conjugation on Polycation-Mediated siRNA Delivery to Orthotopic Pancreatic Tumors
Favorite
12:30 PM – 1:30 PM
ET
(T1230-03-14) Regional Bile Salt and Lipid Concentrations in the Rat Small Intestine: A Comparison between the Lumen and the Mucus Layer
Favorite
12:30 PM – 1:30 PM
ET
(T1230-03-15) Colon Targeted Ibrutinib Amorphous Solid Dispersions for the Treatment of Colorectal Cancer
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12:30 PM – 1:30 PM
ET
(T1230-03-16) How to Improve in Solubility of Water-Insoluble Cyclic Peptide with HA Nanogel : Over 100,000-Fold Solubilization
Favorite
12:30 PM – 1:30 PM
ET
(T1230-03-18) Development of a UV Imaging Method for Characterization of Intra-Tumoral Injectables Using cAMP as Model Substance
Favorite
12:30 PM – 1:30 PM
ET
(T1230-04-19) Insights into the Impact of Interplay of Drug Loading and Buffer Capacity on the Release of Hydroxypropyl Methyl Cellulose Acetate Succinate (HPMCAS)-Based Dispersions
Favorite
12:30 PM – 1:30 PM
ET
(T1230-04-20) Theranostics Peptide Functionalized Graphene Oxide Quantum Dots for Targeted Detection and Treatment of Colorectal Cancer
Favorite
12:30 PM – 1:30 PM
ET
(T1230-04-21) In Vitro Cytotoxicity and Biodistribution Study of Oxaliplatin-Loaded Multivesicular Liposomal Depot
Favorite
12:30 PM – 1:30 PM
ET
(T1230-04-22) 3D-Printed Drug-Eluting Scaffolds for Mechanical Support and Regeneration: A Personalized Approach to Implant-associated Surgical Site Rehabilitation
Favorite
12:30 PM – 1:30 PM
ET
(T1230-04-23) First-in-Class 3D Printing Technology to Fabricate 6-Thioguanine-Loaded Microparticles for Potential COVID-19 Treatment
Favorite
12:30 PM – 1:30 PM
ET
(T1230-05-25) Applying Conformational Dynamics in the Evolution of Enzymes for Biocatalysis
Favorite
12:30 PM – 1:30 PM
ET
(T1230-05-26) 5' Untranslated Region Secondary Structures and Antisense Oligonucleotides Regulate mRNA Translation
Favorite
12:30 PM – 1:30 PM
ET
(T1230-05-27) Neutrophil Extracellular Traps (NETs) Targeting Strategies with Monoclonal Antibody (2C5)
Favorite
12:30 PM – 1:30 PM
ET
(T1230-05-28) Discovery of Peptides to Target Lung Epithelia from Cystic Fibrosis Patients
Favorite
12:30 PM – 1:30 PM
ET
(T1230-05-29) Curcumin as a Repurposed Adjuvant to Overcome Antibiotic Resistance in
Pseudomonas aeruginosa
,
Burkholderia cenocepacia
and
Burkholderia multivorans
Clinical Isolates
Favorite
12:30 PM – 1:30 PM
ET
(T1230-06-31) Transforming Multi-particle Populations with Normal Size Distribution into Mega Beads with Discrete Sizes and Precise Drug Strengths: Surface Area and Rate of Drug Deposition as Critical Parameters
Favorite
12:30 PM – 1:30 PM
ET
(T1230-06-32) Intentionally Made Amorphous Substance to Quantify Unintentionally Produced Amorphous Materials: Decades of Hands-On Experience
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12:30 PM – 1:30 PM
ET
(T1230-06-33) Roadmap for Assessing Analytical Similarity: Case Study of Mab Biosimilar
Favorite
12:30 PM – 1:30 PM
ET
(T1230-06-34) Characterization and Comparison of Biorelevant Simulated Airway Mucus Models to Improve the Development of In Vitro Dissolution and Diffusion Assays for Aerosols
Favorite
12:30 PM – 1:30 PM
ET
(T1230-07-37) Using Enzymes to Accelerate PS80 Degradation and Elucidate Mechanistic Impacts of PS80 Degradation on Biologics Drug Product Quality
Favorite
12:30 PM – 1:30 PM
ET
(T1230-07-38) Polymeric Chloroquine as an Oral Chemopreventive Agent for Colorectal Cancer
Favorite
12:30 PM – 1:30 PM
ET
(T1230-07-39) Application of Film Coating Systems to Hide Dark Spots on Multivitamin Tablets
Favorite
12:30 PM – 1:30 PM
ET
(T1230-07-40) Investigation of the Impact of Manufacturing Parameters on the Mechanism of Formation of Naltrexone-PLGA Microparticles with SSNMR
Favorite
12:30 PM – 1:30 PM
ET
(T1230-07-41) How to Maintain Drug Stability During Twin-Screw Melt Granulation
Favorite
12:30 PM – 1:30 PM
ET
(T1230-07-42) Characterizing Potency of Model AAVs Using Imaging Flow Cytometry
Favorite
12:30 PM – 1:30 PM
ET
(T1230-08-43) In Vitro Assessment of Cooling Potential of the Topical Gel System and Influence of Inactive Ingredients
Favorite
12:30 PM – 1:30 PM
ET
(T1230-08-45) Multiscale Thermo-Kinetic Aging Model of Complex Systems: Application to Device Materials and Interfaces including Implications in Drug Stability
Favorite
12:30 PM – 1:30 PM
ET
(T1230-08-47) Leveraging Extemporaneous Preparation to Accelerate the Clinical Evaluation of an Injectable Suspension
Favorite
12:30 PM – 1:30 PM
ET
(T1230-09-49) Validation of an MFLC-MS/MS Assay for the Quantitative Analysis of a Novel Peptide, AT-01, Extracted from K
2
EDTA Plasma
Favorite
12:30 PM – 1:30 PM
ET
(T1230-09-51) Direct Monitoring of DNA Plasmid Concentration and the Extent of Plasmid-Liposome Complexation Using 2
nd
Derivative Fiber-Optic UV Spectroscopy
Favorite
12:30 PM – 1:30 PM
ET
(T1230-09-52) A Sensitive Solution for Quantification of Anti-sense Oligonucleotides (ASOs) in Rat Plasma Using High-Resolution Mass Spectrometry
Favorite
12:30 PM – 1:30 PM
ET
(T1230-09-53) Novel LC-MS/MS Analyses for Glucagon-Like Peptide-1 (GLP-1) Analogs, Liraglutide, Lixisenatide, and Semaglutide, and Pharmacokinetic Evaluation in Rats
Favorite
12:30 PM – 1:30 PM
ET
(T1230-10-55) Insulin-Like Growth Factor 1 Modulates Transport Activity, Protein Expression, and SUMOylation of Human Organic Anion Transporter 4 through Protein Kinase B Signaling Pathway
Favorite
12:30 PM – 1:30 PM
ET
(T1230-10-56) Liver-Specific Coactivator ARGLU1 is Required for Selected In Vivo PPARα-Regulated Pathways
Favorite
12:30 PM – 1:30 PM
ET
(T1230-10-57) Potentiating mRNA Delivery through Optimization of Novel Ionizable Lipid Formulations
Favorite
12:30 PM – 1:30 PM
ET
(T1230-10-58) AI/ML-Driven In Silico Modeling of the COVID-19 Infection for Accelerated Drug Repurposing and Personalized Therapy
Favorite
12:30 PM – 1:30 PM
ET
(T1230-10-59) Discovery of Anti-LAG-3 Peptides for Cancer Immunotherapy
Favorite
12:30 PM – 1:30 PM
ET
(T1230-10-60) Membrane-Bound Double-Stranded RNAs as a Potential Biomarker for Regenerative Therapy
Favorite
12:30 PM – 1:30 PM
ET
(T1230-12-67) Stabilize and Formulate Yeast-Based Immunobiologics by Lyophilization for Oral Delivery
Favorite
12:30 PM – 1:30 PM
ET
(T1230-12-68) Formulation of PEGylated Liposomes to Reduce Vancomycin Induced Kidney Injury: A Rat Study
Favorite
12:30 PM – 1:30 PM
ET
(T1230-12-69) Impact of Aluminum Oxide Nanocoating on Release Behavior of Posaconazole/HPMCAS Amorphous Solid Dispersions
Favorite
12:30 PM – 1:30 PM
ET
(T1230-12-71) pH Impact on the Suspension Capability of Colloidal MCC
Favorite
12:30 PM – 1:30 PM
ET
(T1230-12-72) Surface-Modified Liposome for Targeted Delivery of Docetaxel: Formulation, Characterization, and In Vitro Evaluation
Favorite
1:30 PM – 2:30 PM
ET
(T1330-01-01) Long-Term Ocular Delivery of Griseofulvin for Therapy of Choroidal Neovascularization
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1:30 PM – 2:30 PM
ET
(T1330-01-02) Application of Bottom-Up Absorption Model for Biopharmaceutics Risk Assessment of Preclinical Candidate
Favorite
1:30 PM – 2:30 PM
ET
(T1330-01-03) Lipid Conjugation to Brush PEG Polymer Delivery Systems Enables Hitchhiking on Lipid Trafficking Pathways to Manipulate Plasma Half-Life, Lymph Uptake and Biodistribution
Favorite
1:30 PM – 2:30 PM
ET
(T1330-01-05) Augmenting In Vitro Dissolution of a Poorly Soluble API with a Multifunctional Lipidic Surfactant in an Orally Disintegrating Tablet
Favorite
1:30 PM – 2:30 PM
ET
(T1330-01-06) Scaled-Up Production of High Drug Loading and Dissolution Enabling Lumefantrine Granules
Favorite
1:30 PM – 2:30 PM
ET
(T1330-02-07) A Novel Whole-Brain Imaging Pipeline for High Resolution Spatial and Temporal Measurements of Amyloid-Beta Plaque Dynamics in Pre-clinical Alzheimer’s Disease Animal Models
Favorite
1:30 PM – 2:30 PM
ET
(T1330-02-08) Pharmacokinetics of Speciofoline, a Minor Kratom Alkaloid in Sprague-Dawley Rats
Favorite
1:30 PM – 2:30 PM
ET
(T1330-02-09) Age-Dependent Skeletal Muscle Response to Long-Term Clofazimine Treatment
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1:30 PM – 2:30 PM
ET
(T1330-02-10) A PKPD Model to Predict the Therapeutic Index of Bispecific Antibody Targeting MerTK in Preclinical Mouse Model
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1:30 PM – 2:30 PM
ET
(T1330-02-11) Assessing Cutaneous Pharmacokinetics of Tazarotene Using Coherent Raman Imaging
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1:30 PM – 2:30 PM
ET
(T1330-02-12) Fed State Intestinal Drug Solubility: The Behaviour of Acidic Drugs
Favorite
1:30 PM – 2:30 PM
ET
(T1330-03-13) Fabrication and In Vivo Evaluation of 3D Printed Biocompatible Dissolvable Microneedle Patch
Favorite
1:30 PM – 2:30 PM
ET
(T1330-03-14) Study on the Impact of Tablet Compression Parameters for a Directly Compressible Formulation Containing Model Low Dose API
Favorite
1:30 PM – 2:30 PM
ET
(T1330-03-15) Exploring Paclitaxel Loaded Adenosine Conjugated PEGylated PLGA Nanoparticles for Targeting Triple-Negative Breast Cancer
Favorite
1:30 PM – 2:30 PM
ET
(T1330-03-16) Design of a Personalized Nasal Device (Matrix-Piston Device, MPD) for Nose-to-Brain Delivery: A 3D-Printing Application
Favorite
1:30 PM – 2:30 PM
ET
(T1330-03-17) Formulating Adenosine for Localized Delivery
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1:30 PM – 2:30 PM
ET
(T1330-04-19) Developability Assessment as an Early De-risking Tool for Biopharmaceuticals: Case Study with Fusion-Proteins
Favorite
1:30 PM – 2:30 PM
ET
(T1330-04-20) Hydrodynamic Robustness of New Hydroxypropyl Cellulose Grade for Modified Release Matrix Systems
Favorite
1:30 PM – 2:30 PM
ET
(T1330-04-21) Lipid Core Nanocapsules for Drug Delivery of Antimicrobials
Favorite
1:30 PM – 2:30 PM
ET
(T1330-04-22) N-acetylcysteine-Loaded Magnetite Chitosan Microparticle (NMCP) Part Ⅱ: In Vitro and In Vivo Study to Confirm the Nitrate Adsorption Behavior
Favorite
1:30 PM – 2:30 PM
ET
(T1330-04-23) Amorphous Powder for Nasal Delivery: Intranasal Naloxone Powder for Treating Opiod Overdose
Favorite
1:30 PM – 2:30 PM
ET
(T1330-04-24) Preparation and Characterization of a New Sweet Salt of Berberine
Favorite
1:30 PM – 2:30 PM
ET
(T1330-05-25) Role of Cancer-Associated Fibroblasts in Lung Cancer Chemoresistance
Favorite
1:30 PM – 2:30 PM
ET
(T1330-05-26) Transdermal Delivery of Nicotinamide Mononucleotide Using Dissolvable Microneedles as a Possible Treatment for Aging-Related Diseases
Favorite
1:30 PM – 2:30 PM
ET
(T1330-05-27) Utilizing Tiny-TIM to Assess the Food Effect on the Absorption of Orally Administered Drugs
Favorite
1:30 PM – 2:30 PM
ET
(T1330-05-28) Prenatal E-Cigarette Use Disrupts Postnatal Blood-Brain Barrier (BBB) Integrity and Worsens Ischemic Stroke Outcomes- Implications on Brain Drug Delivery
Favorite
1:30 PM – 2:30 PM
ET
(T1330-05-29) A Promising Protein Therapeutic Candidate for the Treatment of Cocaine Toxicity in the Presence of Alcohol
Favorite
1:30 PM – 2:30 PM
ET
(T1330-06-31) Development of Cell-Based Bioassays for Measuring the Potency of Biological Drug Products
Favorite
1:30 PM – 2:30 PM
ET
(T1330-06-32) Identification and Control Strategy of Diastereomer Impurities in API Produced via Biocatalytic Cascade
Favorite
1:30 PM – 2:30 PM
ET
(T1330-06-33) Extensive Characterization of Spray Dry Solution Atomization for HPMCAS Placebo Solutions by Optical Patternation, Phase Doppler Analysis, and Spray Velocity
Favorite
1:30 PM – 2:30 PM
ET
(T1330-06-35) Automated Online Agglomeration Detection Using Shadowgraph Imaging Analysis during Dissolution Testing of Ibuprofen Powder in USP 4 Flow-Through Apparatus
Favorite
1:30 PM – 2:30 PM
ET
(T1330-07-37) Coexistent API-Polymer Halogen and Hydrogen Bonds in Amorphous Solid Dispersions Affect Drug Solubility and Miscibility
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1:30 PM – 2:30 PM
ET
(T1330-07-38) Stimulated Raman Scattering (SRS) Microscopy and Deep Learning: Novel Pharmacokinetic Approach for Evaluation of Topical Bioequivalence
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1:30 PM – 2:30 PM
ET
(T1330-07-39) Influence of Solid Content and Plasticizer in Formulation of Hypromellose Oral Thin Film – Part 1
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1:30 PM – 2:30 PM
ET
(T1330-07-40) An Oral Lipid Nanocomplex Incorporating BRD4 PROTAC and Vemurafenib Overcomes BRAF Inhibitor Resistance in Malignant Melanoma In Vivo
Favorite
1:30 PM – 2:30 PM
ET
(T1330-07-41) Using Different Approaches for Evaluation of Aerodynamic Particle Size Distribution Data in Cascade Impaction Test for Orally Inhaled Drug Products (OIDPs) Bioequivalence
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1:30 PM – 2:30 PM
ET
(T1330-08-43) Interaction Effects of Wet Granulation Process Parameters on Granule Size and Dissolution Performance of a High Drug Load Product Manufactured in a High-Shear Mixer
Favorite
1:30 PM – 2:30 PM
ET
(T1330-08-44) Feasibility of Spray Drying Biotherapeutics: A Material Sparing Screening Process
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1:30 PM – 2:30 PM
ET
(T1330-08-46) Compendial Strategy to Update Asbestos Testing Methods for Quality Control of USP Talc
Favorite
1:30 PM – 2:30 PM
ET
(T1330-08-47) Effect of Particle Size and Distribution on the Dissolution Profile of Fenofibrate Capsules
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1:30 PM – 2:30 PM
ET
(T1330-08-48) Titanium Dioxide Free Color Mixtures for Use in Pharmaceutical Drug Products: A Manufacturing Performance Evaluation of the Alternatives
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1:30 PM – 2:30 PM
ET
(T1330-09-50) Quantitative Determination of Arsenic in Dog Blood and Human Blood by Inductively Coupled Plasma Mass Spectrometry (ICP-MS) for Arsenic Drug Development in Pre-Clinical and Clinical Studies
Favorite
1:30 PM – 2:30 PM
ET
(T1330-09-51) Laboratory Validation of a Neurofilament Light Chain (NfL) Clinical Trial Assay for Applications in Neurological Diseases Testing Services
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1:30 PM – 2:30 PM
ET
(T1330-09-52) Comparative Evaluation of Colorimetric, Chromatographic, and Electrochemical Techniques for Hydrogen Sulfide Quantification
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1:30 PM – 2:30 PM
ET
(T1330-09-53) Achieving the Ultimate Laboratory Flexibility with a Four Channel Multi-Method Enabled Multiplexing Liquid Chromatography Mass Spectrometry Platform
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1:30 PM – 2:30 PM
ET
(T1330-09-54) Improvements in Sensitivity for Bioanalysis of Warfarin Using a Prototype Tandem Quadrupole Mass Spectrometer
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1:30 PM – 2:30 PM
ET
(T1330-10-55) TP53 Codon 72 Polymorphism Modulates Macrophage Polarization through Altered PI3K/Akt Signaling Pathways
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1:30 PM – 2:30 PM
ET
(T1330-10-56) Effect of Lipid Composition on the Atheroprotective Properties of HDL-Mimicking Micelles
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1:30 PM – 2:30 PM
ET
(T1330-10-57) Female Sex Hormones Alter GHB Toxicokinetics
Favorite
1:30 PM – 2:30 PM
ET
(T1330-10-58) Design and Development of Protease-Activated Chemically Self-Assembled Nanorings (Pro-CSANs) for Cancer Immunotherapy
Favorite
1:30 PM – 2:30 PM
ET
(T1330-10-59) Statins Constrict Resistance-Size Cerebral Arteries by Stimulating L-type Ca
2+
Channels
Favorite
1:30 PM – 2:30 PM
ET
(T1330-11-61) System Optimization to Mitigate Signal Suppression While Autonomously Running Multiple LC/MS/MS Methods in for SiRNAs, Peptides and Small Molecules in Sequence
Favorite
1:30 PM – 2:30 PM
ET
(T1330-11-62) Regulatory Assessments for In Vivo Pharmacokinetic Abuse Deterrence Studies in Generic Drug Product Applications
Favorite
1:30 PM – 2:30 PM
ET
(T1330-11-63) A Novel Transcellular Assay for Monocarboxylate Transporter 10 (MCT10)
Favorite
1:30 PM – 2:30 PM
ET
(T1330-11-64) Physiologically Based Pharmacokinetic Model for Miltefosine in Mice
Favorite
1:30 PM – 2:30 PM
ET
(T1330-11-65) Influence of Formulation Factors on Potency of Topical Corticosteroid Creams by Fitting Pharmacodynamic Data to the E
max
Model
Favorite
1:30 PM – 2:30 PM
ET
(T1330-12-67) Fourier Transform Infrared Spectroscopy (FT-IR) of Lyophilized RNA
Favorite
1:30 PM – 2:30 PM
ET
(T1330-12-68) Folic Acid Conjugated Lipid Nanoparticles containing CORM-2 for Inflammation-Targeted Carbon Monoxide Delivery
Favorite
1:30 PM – 2:30 PM
ET
(T1330-12-70) API-Sparing KinetiSol Processing Approach to Support Discovery Chemistry
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1:30 PM – 2:30 PM
ET
(T1330-12-71) Quality and Processability Parameters Prediction for a Direct Compressible Tablet Powder Mix
Favorite
1:30 PM – 2:30 PM
ET
(T1330-12-72) Investigation of Polymers for SLS 3D-Printing of Solid Oral Dosage Forms
Favorite
1:30 PM – 2:30 PM
ET
(T1330-06-34) A Powder Tabletability Equation
Favorite
2:30 PM – 3:30 PM
ET
(T1430-01-01) Development of Sublingual Tablets Containing Promethazine Hydrochloride for Paediatric Applications
Favorite
2:30 PM – 3:30 PM
ET
(T1430-01-02) Coarse-Grained Molecular Dynamics Simulations of ssDNA Loaded Adeno-Associated Virus
Favorite
2:30 PM – 3:30 PM
ET
(T1430-01-03) Coaxial Electrospun Fabric as a Drug Delivery Platform for Mafenide Acetate and Polyhexanide to Combat Burn Wound-Associated Infection
Favorite
2:30 PM – 3:30 PM
ET
(T1430-01-04) Animal Pharmacokinetic Studies of Cannabidiol Nanoformulation
Favorite
2:30 PM – 3:30 PM
ET
(T1430-01-05) Qualitative and Quantitative Analysis of Drug Diffusion, Into and Across Dermaplaned Skin
Favorite
2:30 PM – 3:30 PM
ET
(T1430-02-08) Spectinamide 1599 Exposure in Lung, ELF and Plasma after Passive Inhalation in Mice
Favorite
2:30 PM – 3:30 PM
ET
(T1430-02-09) Evaluating the Effect of Nano-Immulina in Mice Peripheral Blood with Emphasis in Immunophenotyping and Neutrophil Phagocytosis
Favorite
2:30 PM – 3:30 PM
ET
(T1430-02-10) A Minimal PBPK-PD Model to Predict PK, PD, and Efficacy of Anti-CCR8 Antibody in Mice
Favorite
2:30 PM – 3:30 PM
ET
(T1430-02-11) The Impact of Advanced Age on Bacterial Drug Degradation in the Lower Intestine and the Usefulness of Data in Fecal Material
Favorite
2:30 PM – 3:30 PM
ET
(T1430-02-12) Pharmacokinetics and Biliary Excretion of a Freeze-Dried Paclitaxel Prodrug-Loaded Polymeric Micelle Delivery System
Favorite
2:30 PM – 3:30 PM
ET
(T1430-03-13) A Novel Therapeutic Platform for Improved Glioblastoma Treatment
Favorite
2:30 PM – 3:30 PM
ET
(T1430-03-14) In Vitro Permeation Studies Combined with Microdialysis Sampling Allow Mechanistic Insights into the Dynamic Dissolution-/ Bioconversion-/ Permeation-Behavior of the Prodrug Fosamprenavir
Favorite
2:30 PM – 3:30 PM
ET
(T1430-03-16) Comparison of Film Coating Weight, Color Uniformity and Throughput of Tablets Coated in High Speed Semi Continuous Coater and Traditional Pan Coater Using Titanium Dioxide Free Film Coating Systems
Favorite
2:30 PM – 3:30 PM
ET
(T1430-03-17) The Sustained Release Potential of MCM-41 versus SBA-16 Serving as Entrapment Carriers after Amine Surface Functionalization
Favorite
2:30 PM – 3:30 PM
ET
(T1430-03-18) Application of MicroCoat
TM
Technology to Mask Bitter Taste of Amodiaquine and Artesunate in a Combination Antimalarial Formulation for Oral Paediatric Administration
Favorite
2:30 PM – 3:30 PM
ET
(T1430-04-19) Characterization of Aerosolized Droplets Using a 3D Printed Device for Small Animal Nose-to-Brain Drug Administration
Favorite
2:30 PM – 3:30 PM
ET
(T1430-04-20) Formulation and Ex Vivo Permeability of Diphenhydramine Orally Dissolving Films (ODFs) for Buccal Drug Delivery
Favorite
2:30 PM – 3:30 PM
ET
(T1430-04-21) In Vitro Evaluation of Foamable Diclofenac Sodium Loaded Topical Microemulsion
Favorite
2:30 PM – 3:30 PM
ET
(T1430-04-22) Developing an Inhaled Nano-Emulsion for Repurposing an Herbal Drug for Non-small Cell Lung Cancer
Favorite
2:30 PM – 3:30 PM
ET
(T1430-04-23) Building a Chemical Space Map for In Silico Prediction of Supersaturation by Mesoporous Silica
Favorite
2:30 PM – 3:30 PM
ET
(T1430-06-31) Development of a Lyophilized Single Vial Adjuvanted Sub-unit Vaccine for Bed Side Reconstitution
Favorite
2:30 PM – 3:30 PM
ET
(T1430-06-32) Reverse Engineering of Invega Sustenna
®
(paliperidome palmitate suspension)
Favorite
2:30 PM – 3:30 PM
ET
(T1430-06-33) Downstream Processing of Itraconazole:HPMCAS Amorphous Solid Dispersion: From Hot-Melt Extrudate to Tablet Using a Quality by Design Approach
Favorite
2:30 PM – 3:30 PM
ET
(T1430-06-34) Chemical Imaging by Raman Spectroscopy: A Powerful Analytical Technique for Surface Morphology Investigation of Inhaled Products
Favorite
2:30 PM – 3:30 PM
ET
(T1430-06-35) Investigation of In Vitro Buccal Permeation Mechanisms of Compound A
Favorite
2:30 PM – 3:30 PM
ET
(T1430-07-37) NanoFabTx™: A Step-by-Step Quick Screening Platform for Liposomal Drug Delivery Systems
Favorite
2:30 PM – 3:30 PM
ET
(T1430-07-38) Different Pharmacokinetics and Local Inflammation between Injectable Aqueous Drug Suspension and Oil Suspension
Favorite
2:30 PM – 3:30 PM
ET
(T1430-07-39) Modifying Drug Release from Microparticles Prepared by Spray Drying Using a 3-Fluid Nozzle
Favorite
2:30 PM – 3:30 PM
ET
(T1430-07-40) Preformulation Studies on Two Novel Indole-2-Carboxamides Highly Potent Against Nontuberculous Mycobacteria
Favorite
2:30 PM – 3:30 PM
ET
(T1430-07-41) Preparation of Telmisartan Nanoparticles by the Supercritical Antisolvent Process: Effect of Particle Size on the Dissolution and Oral Bioavailability
Favorite
2:30 PM – 3:30 PM
ET
(T1430-07-42) Preparation and Characterization of Orally Disintegrating Tablets of Caffeine, Verapamil and Atenolol
Favorite
2:30 PM – 3:30 PM
ET
(T1430-08-43) Rapid Residual Solvent Analysis using SIFT-MS for USP Method
Favorite
2:30 PM – 3:30 PM
ET
(T1430-08-44) Application of Machine Learning Tools for Predicting Impact of Punch Cup Depth on Tablet Capping
Favorite
2:30 PM – 3:30 PM
ET
(T1430-08-45) Green Chemistry Initiative for Formulating, Pressing and Evaluating Tablets in Low-Resource Settings
Favorite
2:30 PM – 3:30 PM
ET
(T1430-08-46) Using Raman Mapping to Detect and Identify Challenging Degradation Products and Complex Drug-Drug Interactions in a Tablet
Favorite
2:30 PM – 3:30 PM
ET
(T1430-08-47) Engineering 3D Printed Microfluidic Chips for the Fabrication of Nanomedicines
Favorite
2:30 PM – 3:30 PM
ET
(T1430-08-48) Customized Fast-Dissolving Orodispersible Films Using Extrusion-Based 3D-Printing
Favorite
2:30 PM – 3:30 PM
ET
(T1430-09-50) Toward the Use of In Vitro Animal Matrix Stress Models to Predict In Vivo Stability of Oligonucleotides
Favorite
2:30 PM – 3:30 PM
ET
(T1430-09-51) Comparability of Glycosylation, Antigen Binding and Fc Effector Function for Three Anti-TNF-a Therapeutics
Favorite
2:30 PM – 3:30 PM
ET
(T1430-09-52) Hybrid-LC-MS/MS Method for Simultaneous Quantification of Two COVID-19 Biotherapeutic Monoclonal Antibodies in Human Serum
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2:30 PM – 3:30 PM
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(T1430-09-53) Comprehensive AAV Characterizations Using HRMS: Peptide Mapping, Capsid Proteins, Intact ssDNA, and Intact Virus
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2:30 PM – 3:30 PM
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(T1430-09-54) A Targeted LC-MS/MS Method for Quantitative Tissue Distribution Analysis (QTDA) of Metabolomics in Tumors using Laser Microdissection
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2:30 PM – 3:30 PM
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(T1430-10-55) Development of a Novel Tocotrienol Analogue, Tocoflexol, as a Powerful Radioprotective Agent
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2:30 PM – 3:30 PM
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(T1430-10-56) Increasing the Productivity of Oligonucleotide Purification through Column Scaling and Method Optimization
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2:30 PM – 3:30 PM
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(T1430-10-57) New Developments in the MolMeDB Database of Membrane Interactions of Small Molecules
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2:30 PM – 3:30 PM
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(T1430-10-58) Tissue Distribution using Quantitative Whole Body Autoradiography (QWBA) of [
14
C]-Paclitaxel in Tumor Bearing Mice
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2:30 PM – 3:30 PM
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(T1430-10-59) Development of a Broadly Active Influenza Intranasal Vaccine Adjuvanted with Self-Assembled Particles Comprised of Mastoparan-7 and CpG
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2:30 PM – 3:30 PM
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(T1430-11-61) SNP-630, a Novel Compound with Multiple Mechanisms, Reverses Non-alcoholic Steatohepatitis-Derived Liver Injury and Fibrosis
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2:30 PM – 3:30 PM
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(T1430-11-62) MRP1 Knockdown in NCI-H441 Cells to Generate an Organotypic In Vitro Model for Pulmonary Drug Disposition Studies
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2:30 PM – 3:30 PM
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(T1430-11-63) Development of Accelerated Transdermal Diffusion model for In Vitro Permeation Testing of Topical Pharmaceuticals
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(T1430-11-64) SARS-CoV-2 Infection Dysregulates Drug Metabolism and Transport
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2:30 PM – 3:30 PM
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(T1430-12-67) Development of Topical Foam Formulation for Decontamination Post Exposure to Lewisite and Extended Antidote Delivery upon Reapplication
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(T1430-12-68) Inhaled Ponatinib-Cyclodextrin Complex for Anticancer Effects on Non-Small Cell Lung Cancer
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(T1430-12-70) Inhaled Albumin Nanoparticles as a Delivery Strategy to Improve the Risk/Benefit Ratio of PDE-4 Inhibitors
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2:30 PM – 3:30 PM
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(T1430-01-06) Fabrication of pH-Responsive Acetalated Dextran Nanoparticles Using Flash Nanoprecipitation for Intracellular Delivery of Payloads
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2:30 PM – 3:30 PM
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(T1430-04-24) Investigating Critical Parameters for Using Phenylarsine Oxide as a Surrogate to Assess Percutaneous Absorption of Arsenicals
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3:30 PM – 4:30 PM
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(T1530-01-02) Biopharmaceutical Modeling of Food Effect – Exploring a Role for Dietary Fat
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(T1530-01-03) Feeling the Pressure: Polymorphism, Particle Size and Morphology Control Through Nanoparticle Crystallization Using Controlled Expansion of Supercritical Solutions
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3:30 PM – 4:30 PM
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(T1530-01-05) Pectin as a Natural Tablet Coating Alternative
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3:30 PM – 4:30 PM
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(T1530-01-06) Properties and Printability of Recycled Pharmaceutical Powder Blend in SLS 3D Printing
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3:30 PM – 4:30 PM
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(T1530-03-13) Characterization of Swelling Behavior of HPMC alone and in Combination with Some Ionic Polymers
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(T1530-03-14) LHRH-Targeted Nano-repurposed Drug Carriers for Triple Negative Breast Cancer Treatment
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3:30 PM – 4:30 PM
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(T1530-03-15) A Comparison of Cocrystals of a Poorly Water-Soluble, Fast Recrystallizing Drug with Its Amorphous Solid Dispersions
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3:30 PM – 4:30 PM
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(T1530-03-17) Imaging Analysis of Corneal Fluorescein Permeation Kinetics
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3:30 PM – 4:30 PM
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(T1530-04-19) Hydrophobic Ion Pair for the Oral Delivery of Leucine-Enkephalin
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3:30 PM – 4:30 PM
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(T1530-04-20) Oral Drug Delivery Strategy Using Bile Acid Decorated Nanoparticles
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(T1530-04-21) Dose Dependency Effect on the Skin Permeation of Polar and Non-Polar Compounds
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3:30 PM – 4:30 PM
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(T1530-04-22) N-acetylcysteine-Loaded Magnetite Chitosan Microparticle (NMCP) Part I: Preparation of Inhalable Chitosan-Fe
3
O
4
Composite for Removal of Nitrate of Particulate Matter
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3:30 PM – 4:30 PM
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(T1530-04-23) Determination of Binding Constants between Diflunisal and Trazodone and Several Excipients
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(T1530-04-24) Compatibility Study between Fluoroquinolones and Carbopol
®
Polymers Used in the In Situ Gel Forming Delivery Systems
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3:30 PM – 4:30 PM
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(T1530-05-25) Chloroquine, Hydroxychloroquine Modulates Protein Expression, Transport Function and Ubiquitination of Organic Anion Transporter 3
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(T1530-05-26) In Vitro Models of the Human Oral Mucosa for Screening Novel Formulations and Adjuvants for Film-Based Vaccines
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(T1530-05-27) Co-delivery of siRNA and Chemotherapeutic Drug Using 2C5 Antibody Modified Dendrimer-Based Mixed Micelles for the Treatment of Multidrug Resistant Cancers
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3:30 PM – 4:30 PM
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(T1530-05-29) Nervonic Acid - A Potential Therapeutic Targeting Mitochondrial Dysfunction and Cellular Oxidative Stress
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3:30 PM – 4:30 PM
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(T1530-06-31) Determining the Minimum Required Thickness of Enteric Coatings by Means of Optical Coherence Tomography
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3:30 PM – 4:30 PM
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(T1530-06-32) Immunogenicity Risk Assessment for Host Cell Proteins in Vaccines and Biologics
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3:30 PM – 4:30 PM
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(T1530-06-33) Gradient Recycling Chromatography for the Preparation of Pure Target Compounds Present in Highly Complex Mixtures
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(T1530-06-34) Seeing is Believing: A Microscopic “Google Earth” View of Extended-Release Claritin Formulation
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(T1530-06-35) Principal Component Analysis of Granule Size Distributions for Development of Continuous Twin-Screw Granulators
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3:30 PM – 4:30 PM
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(T1530-07-37) Attenuating Neuroinflammation and Promoting Neurogenesis through Co-delivery of Curcumin and Brain Derived Neurotrophic Factor (BDNF) for the Management of Alzheimer’s disease
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3:30 PM – 4:30 PM
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(T1530-07-38) Synthesizing Cisplatin Pt (IV) Derivatives for Reducing Systemic Toxicity and Enhancing Anticancer Efficacy in Triple-Negative Breast Cancer
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3:30 PM – 4:30 PM
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(T1530-07-41) Comparison of Trehalose and Sucrose in Preserving and Stabilizing Lyophilized Therapeutic Proteins
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3:30 PM – 4:30 PM
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(T1530-07-42) Application of Alternative Metallic Stearates as Lubricants in Pharmaceutical Tablets
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3:30 PM – 4:30 PM
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(T1530-09-50) Pharmacokinetics and Brain Distribution of the Therapeutic Peptide Semaglutide by a Novel Liquid Chromatography-Tandem Mass Spectrometry
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3:30 PM – 4:30 PM
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(T1530-09-51) Novel HILIC-LC-MS Method for Quantification of Ketone Bodies (beta-hydroxybutyrate and acetoacetate) in Human Plasma
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3:30 PM – 4:30 PM
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(T1530-09-52) Impact of Autosampler Design on Carryover Performance During Method Migration
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3:30 PM – 4:30 PM
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(T1530-09-53) Quantitating the Concentration of DNA Plasmid Using 2
nd
Derivative Fiber-Optic UV Spectroscopy and Intercalating Dye
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3:30 PM – 4:30 PM
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(T1530-09-54) Sensitive Bioanalysis of Anti-sense Oligonucleotides through Mitigation of Non-specific Binding and Improved LC-MS/MS Performance
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3:30 PM – 4:30 PM
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(T1530-11-61) Physiologically-Based Pharmacokinetic Model to Predict Milk Drug Concentrations of Breast Cancer Resistance Protein Substrates
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3:30 PM – 4:30 PM
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(T1530-11-62) Effect of Intestinal Precipitation on Cinnarizine Plasma Profile in Fasted State Employing Biorelevant In Vitro Tools and GastroPlus
®
Modeling
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3:30 PM – 4:30 PM
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(T1530-11-63) A Platform for Mechanistic Modelling of Subcutaneous Administration with the Effect of Immunogenicity within the Open Systems Pharmacology Framework
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3:30 PM – 4:30 PM
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(T1530-11-64) Quantifying the Disparate Impact of Eligibility Criteria on Recruiting Diverse Patients for a Clinical Trial in Non-Hodgkin’s Lymphoma
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3:30 PM – 4:30 PM
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(T1530-12-67) Remote Loading of Auto-Antigens in PLGA Nanoparticles for the Treatment of Autoimmune Diseases
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3:30 PM – 4:30 PM
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(T1530-12-68) Preparation and Evaluation of Sorafenib Nanosuspensions Using High Pressure Homogenization Technique for Improved Oral Bioavailability
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3:30 PM – 4:30 PM
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(T1530-12-69) Shear-Thinning Injectable Hyaluronic Acid Hydrogels for Diabetic Wound Healing
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3:30 PM – 4:30 PM
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(T1530-12-70) In Situ Phase Transition to Liquid Crystal with the GMO and Co-surfactant for Controlled Nasal Mucosa Permeation of Drug
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3:30 PM – 4:30 PM
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(T1530-12-71) Development of a Fixed Dose Combinations Using Double Melt Extrusion Technology
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3:30 PM – 4:30 PM
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(T1530-12-72) Dissolution Rate Increases for Morphine Sulfate Extended-Release Drug Product When Mixed with High pH Soft Food for Long Contact Times
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3:30 PM – 4:40 PM
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(T1530-01-01) Phosphatidylserine Targeting for Enhancing Immunochemotherapy of Cancer
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