Formulation and Delivery
Naoki Yamada, MS
Director Strategy and Operation
FUJIFILM Pharmaceuticals U.S.A., Inc.
Cambridge, Massachusetts
Description: The number of clinical trials of chemotherapeutic agents (chemo) in combination with Immune Checkpoint Inhibitor (ICI) is remarkably growing to improve anti-tumor effects. In this session, we will share preclinical results that liposome formulations can boost synergistic effect of chemo with ICI by stimulating cancer immunity. In addition, the challenges on early-stage development from bench top to the 1st in human of liposome formulations: species difference and CMC, and solutions will be presented and discussed.