Formulation and Delivery
Tobias Rosenkranz, PhD
Senior Manager, Head of Biomolecule Formulation – Technology & Innovation
MilliporeSigma
Darmstadt, Hessen, Germany
Description: This presentation focuses on the challenges high protein viscosity poses to formulation and manufacturing scientists. The attendee will learn about an excipient portfolio that can reduce viscosity while maintaining protein stability. Additionally, they will learn how highly viscous protein solutions impact tangential flow filtration and how this can be mitigated by using viscosity reducing excipients. A case study will demonstrate how such formulation techniques can lead to a more patient convenient drug product (high concentration, low volume) with an improved manufacturability.