Senior Scientist: Research, Development and Innovation Evonik North America, Vancouver, British Columbia, Canada
CARTs are biodegradable, amphiphilic oligomers suitable for the formulation and delivery of nucleic acids, which undergo a pH-dependent self-degradation mechanism. The presentation introduces this novel platform and gives an overview about the underlying concepts and early application data.
Learning Objectives:
To understand the chemistry and underlying principles of a new oligomeric delivery system for nucleic acids.
To understand the challenges associated with transferring oligomer synthesis from academic into industrial settings.
To understand the challenges associated with formulation development of the new oligomeric system.
