Patented High Efficiency conical mill screens improve operational efficiencies - capacities can be increased and milling temperatures reduced without changing or shifting particle size distributions. Screens are interchangeable with older mills, thus ensuring validated processes and results remain unaffected.
Method: Research was completed as a combination of numerical simulations through computation fluid dynamics (CFD) to anticipate air and mass flow; and supported by empirical data derived from a DoE test matrix with various pharmaceutical placebos/actives representing different material properties. DoE tests completed with a Quadro Comil and analyzed primarily with laser diffraction technology.
Results: Both CFD analysis and empirical DoE test results corroborate the improved mass flow (milling efficiency) regardless of the infeed materials' properties and particle characteristics without negatively impacting validated particle size distributions (PSDs). Capacity throughput improvements averaged a 50% increase, with the added benefit of an average 10-15 degree C reduction in milling temperatures.
Learning Objectives:
Understand the productivity benefits of newly patented conical mill screens to their existing or future projects.
Improve their knowledge of how conical screens work and what makes their design uniquely important to their processes
Apply the new screen technology at the R&D stage and how it easily scales-up to pilot-scale and onto a production environment.