A case study using an extended release osmotic capsule to evaluate drug absorption throughout the gastrointestinal tract will be presented. Extended release capsules were rapidly developed and dosed into dogs. In vivo dog data from the extended release capsule provided data critical for development of the human clinical dosage form.
Learning Objectives:
Describe oral extended release dosage form options.
List the benefits of osmotic oral extended release dosage forms.
Demonstrate use of osmotic extended release capsules in an in vivo animal study.
