Molecular analysis of circulating tumor DNA (ctDNA) is being used to monitor disease progression and response to therapy. Ease in collecting blood samples also provides an alternative to solid tissue biopsies for clinical diagnosis or enrolling patients for clinical trials. In my presentation, some of the factors that can affect the results obtained by profiling ctDNA and other tumor specific materials will be discussed. In addition, the presentation will show how data obtained from these can provide useful information for drug development.
Learning Objectives:
Factor needs to be considered prior to sample processing
Assays to be used for profiling ctDNA
Learn about factors other than sample collection that can affect molecular profiling data
Materials other than ctDNA that can provide useful information about disease progression