Charir Pharmacology
Medical University of South Carolina
Kenneth D. Tew is Chair of Pharmacology at the Medical University of South Carolina and the John C. West Chair in Cancer Research at the Hollings Cancer Center. His research addresses fundamental aspects of cancer drug discovery and development, helping to define how redox mechanisms interconnect with essential signaling pathways and how activities of glutathione S-transferases catalyze the forward reaction of S-glutathionylation, a post-translational modification which alters structure/function of a variety of proteins critical to cell growth. Some preclinical studies have translated into clinical trials. Redox pathways and the redox proteome and its associated pathways therefore form a platform for discovery and development. He has been continuously funded through the NIH since 1980, including an earlier Outstanding Investigator Grant and various research foci have been facilitated by leadership roles in cancer therapeutics through each of his Institutional appointments. At MUSC, Dr. Tew leads a COBRE (Centers of Biomedical Research Excellence) grant over the last decade, which has a focus on mentoring junior faculty members towards independence. He continues to participate in review and advisement leadership capacities at the NIH and as a member of multiple Scientific Advisory Boards for a variety of Cancer Centers and Biotechnology companies.
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Monday, October 17, 2022
1:30 PM – 2:30 PM ET