Research Professor
Catholic University of Korea, Republic of Korea
This is Kyoung Sub Kim. I am working as a research professor in the Department of Biotechnology, Catholic University of Korea. I have a research background in the drug delivery system. I have been dealing with various forms of biomaterials such as polysaccharides, peptides/proteins, gadolinium, iron oxide, and stem cells. These biomaterials were chemically modified to produce various types of drug delivery carriers, which can be applied to cancer diagnosis, image-guided therapy, cancer immunotherapy, and diabetes treatment.
I am proficient in the design and formulation of nanomedicine and the analysis of pharmacokinetics and pharmacodynamics. In detail, I can fabricate and characterize the properties of nanomedicine using HPLC, DLS, NMR, IR, and TEM. I have experience in demonstrating interactions with an extracellular receptor and cellular uptake of drugs in vitro through immunocytochemical staining, flow cytometry, and confocal microscopy. I also have experience visualizing in vivo, such as the movement of drugs in the gastrointestinal tract, tumor targeting, and organ distribution using the IVIS imaging system, MRI, and ICP-MS. Through animal experiments, I have developed techniques in organ harvesting including the lymph nodes, blood collection in mice (tail vein, facial vein, and infraorbital vein) and rats (jugular vein without catheterization and tail vein), and lymph cannulation in rats. I can also build tumor and diabetic animal models and evaluate their therapeutic efficacy, toxicity (H&E staining), and immunogenicity (immune cell counting by flow cytometry and ELISA).