Postdoctoral Research Associate
Purdue University
In the last 4 years, I have worked in the Department of Industrial and Physical Pharmacy at Purdue University in support of development of new drug products for Eli Lilly and Co. My self-directed postdoctoral research in the Yeo Lab aims to screen API/ excipient, design implant and injectables of poorly soluble small molecule and biologic drugs by applying various approaches (e.g. solid dispersion, encapsulation, and hot melt extrusion), and evaluate how physicochemical and solid- state properties of a drug product effect the stability and in vitro/vivo performance of controlled, sustained, and continuous infusion release. Prior to my postdoctoral work, my PhD research at the University of Bath in the UK was to formulate nanoparticles and develop analytical methods for biopharmaceuticals, such as insulin, lysozyme, hemoglobin, tetanus toxin C-fragment (TTCF), and TB antigen, which could tolerate up to 100 °C and be used with oral and IV administrations. My research interest has largely focused on formulating and analyzing API/excipient compositions to overcome the challenges in drug delivery. Through my years in designing drug products and studying protein stabilities and fibrin clot, I have acquired a wide range of cross-disciplinary skills of project management, experimental design, and analytical methods, such as SDS-PAGE, HPLC, MS, SEC, CD, DLS, SAXS, microscopy, and in vitro in vivo studies. My ultimate goal is to help live-saving matters by applying physical science to improving drug delivery systems.