teacher
n/a
Beijing
Guanghao Wu
Research Interests
Synthesis and Applications of Biomimetic nanomaterials, Bioanalysis, Inflammation imaging and diagnosis
Education Experience
Dec.2020-Now Postdoc. in Materials Science and Engineering
Beijing Institute of Technology, China
Sep.2016-Dec.2020 Ph.D. in Chemical Engineering and Technology
Beijing Institute of Technology, China
Sep.2013- Jun.2016 M.S. in Biochemistry and Molecular biology
Hebei Normal University, China
Sep.2009- Jun.2013 B.S. in Biological Sciences
Hebei Normal University, China
Research Experience
Ph.D. Objective to develop self-targeting biomimetic platform for imaging and therapy of early atherosclerosis.
1) Molecularly engineered M2 macrophage-derived exosomes with inflammation-tropism and anti-inflammatory capabilities for atherosclerosis imaging and therapy.
2) Self-Driven Biomimetic Magnetosomes for early detection and treatment of atherosclerosis.
M.S. Objective to develop stable thermosensitive in situ gel-forming systems based on the lyophilizate of chitosan/α,β-glycerophosphate salts.
Publications
1) Guanghao Wu; Jinfeng Zhang; Qianru Zhao; Wanru Zhuang; Jingjing Ding; Chi Zhang; Haijun Gao; Daiwen Pang; Kanyi Pu; Haiyan Xie*; Molecularly engineered macrophage-derived exosomes with inflammation tropism and intrinsic heme biosynthesis for atherosclerosis treatment (Hot paper), Angew. Chem. Int. Ed. 2020, 59(10): 4068-4074.
2) Guanghao Wu#; Wei Wei#; Jinfeng Zhang; Weidong Nie; Lan Yuan; Yuanyu Huang; Liping Zuo; Lili Huang; Xiaobo Xi; Haiyan Xie*; A self-driven bioinspired nanovehicle by leukocyte membrane-hitchhiking for early detection and treatment of atherosclerosis, Biomaterials. 2020, (250)119963.
3) Guanghao Wu; Yuan Yuan; Jintian He*; Ying Li; Xiaojing Dai; Baohua Zhao；Stable thermosensitive in situ gel-forming systems based on the lyophilizate ofchitosan/α,β-glycerophosphate salts. Int J Pharm. 2016, 511(1), 560-569.
4) Weidong Nie; Guanghao Wu; Jinfeng Zhang; Lili Huang; Jingjing Ding; Anqi Jiang; Yahui Zhang; Yanhong Liu; Jingchao Li; Kanyi Pu; Haiyan Xie*; Responsive exosome nano-bioconjugates for synergistic cancer therapy (Hot paper), Angew. Chem. Int. Ed. 2020, 59(5): 2018-2022.
5) Weidong Nie; Guanghao Wu; Haizheng Zhong; Haiyan Xie*; Membrane vesicles nanotheranostics systems: opportunities and challenges. Biomed Mater. 2020, (16) 022009.
6) Houli Liu, Lili Huang, Mingchuan Mao, Jingjing Ding, Guanghao Wu, Wenlin Fan, Tongren Yang, Mengjie Zhang, Yuanyu Huang; Haiyan Xie*, Viral Protein-Pseudotyped and siRNA-Electroporated Extracellular Vesicles for Cancer Immunotherapy. Adv Funct Mater. 2020, (30)2006515.
7) Jingjing Ding; Guihong Lu; Weidong Nie; Lili Huang; Yahui Zhang; Wenlin Fan; Guanghao Wu; Houli Liu; Haiyan Xie*, Self-Activatable Photo-Extracellular Vesicle for Synergistic Trimodal Anticancer Therapy. Adv Mater. 2021, (33)2005562.
8) Weidong Nie#; Wei Wei#; Liping Zuo; Chengliang Lv; Fan Zhang; Guihong Lu; Feng Li; Guanghao Wu; Lili Huang; Xiaobo Xi; Haiyan Xie*; Magnetic nanoclusters armed with responsive PD-1 antibody synergistically improved adoptive T-cell therapy for solid tumors, ACS Nano. 2019, 13(2): 1469-1478.
Patents
1）Haiyan Xie, Guanghao Wu, Qianru Zhao, Jinfeng Zhang. Method for the preparation of engineered exosomes with inflammation-tropism and anti-inflammatory capabilities. Patent No.: ZL201911214385.0, authorized on Mar. 27, 2020.
Disclosure information not submitted.
Wednesday, October 19, 2022
3:00 PM – 3:15 PM ET