(24 - Friday) Frequency of Postoperative hyperglycemia and outcomes of hyperglycemic children who underwent repair of congenital cardiac defects in a tertiary care setup of Pakistan.

Find board locations here.

Abstract:

Introduction:
Hyperglycemia is ubiquitous in critically ill children after surgical repair of congenital cardiac defects. Despite heavy burden of congenital cardiac defects in our region, there is a dearth of data determining poor outcomes in post-surgery patients. The results of this study will thereby explore outcomes of hyperglycemia and facilitate early recognition and prompt management of postoperative hyperglycemia that will aid in reducing morbidity and mortality.


Objective:
To determine the frequency of postoperative hyperglycemia and outcomes in hyperglycemic children who underwent repair of congenital cardiac defects.
MATERIALS AND

Method:
This is a descriptive study conducted at CICU of Aga Khan University Hospital during 2020-2021. Glucose levels were monitored within 1st post-operative hour, then at 4th and 8th postoperative hours, followed by once daily monitoring on day 2 and 3. The severity of hyperglycemia was classified as moderate (126-199 mg/dl) and severe (>200 mg/dl) and post-operative outcomes in hyperglycemic children were assessed.

Results: Mean ± SD of age was 40.40±48.63 months. Out of 185 patients, 62.2% were male while 37.8% were female. Hyperglycemia was found to be in 98.4% patients among them 28.6% and 69.7% had moderate and severe hyperglycemia respectively. Hyperglycemia was not found to be significantly associated with duration of mechanical ventilation (p= 0.221) , length of hospital stay (p=0.285) or length of CICU stay (p=0.235). Severity of hyperglycemia is not significantly associated with duration of mechanical ventilation (p= 0.204), length of hospital stay (p=0.117) or length of CICU stay (0.055).

Conclusion:
Hyperglycemia is a frequent finding in children who underwent repair of congenital cardiac defects, and it is not significantly associated with duration of mechanical ventilation, length of hospital or CICU stay. More work needs to be done on association of outcomes of hyperglycemic children because timely diagnosis and correction of hyperglycemia can lead to decrease morbidity.