NP/Associate Clinical Investigator
HonorHealth Research and Innovation Institute
Gayle Jameson is a Nurse Practitioner who has cared for adults living with cancer for more than
40 years. She is certified as an Advanced Oncology Nurse (AOCN) and is especially interested
in the care of patients with pancreatic cancer, early cancer drug development and symptom
management.
In her role as Clinical Investigator at the Oncology Clinical Trials Department, HonorHealth
Research Institute (HRI) in Scottsdale, Arizona, she has been Principal Investigator (PI) on
multiple phase I and investigator initiated studies and Sub-investigator on 80+ phase I and II
anti-tumor clinical trials. She incorporates translational science in clinical trial designs by
working with bench science colleagues at Translational Genomics Institute (TGEN), and as a
member of the SU2C Pancreatic Cancer Dream Team. Gayle also was the site Principal
Investigator on an international study that led to the approval of Onivyde™ plus 5FU and
leucovorin for patients with metastatic pancreatic cancer. She recently published a study in
JAMA Oncology 2020 that demonstrated significant improvement in the overall survival in
patients with advanced pancreatic cancer. Gayle has presented her work nationally and
internationally. As a pioneer of the role of an NP as a Clinical Investigator in early Cancer Drug
Development, she served as Founder and Co-Director of the “Inaugural Oncology Nurse
Practitioner Clinical Investigator Intensive Course”, a collaborative project of HRI and City of
Hope, held at HonorHealth in 2018 and repeated in 2020. Gayle has also been honored as a
recipient of the Oncology Nursing Society’s 2019 Lifetime Achievement Award, and the 2020
Luminary Award in GI Cancers by The Ruesch Center for the Cure of Gastrointestinal Cancers
at Georgetown Lombardi Comprehensive Cancer Center.