University of Texas Southwestern Medical Center
Dallas, Texas, United States
Peter Ly received his B.A. in Biology from Baylor University and earned his Ph.D. in Cancer Biology from UT Southwestern Medical Center. He pursued postdoctoral training at the University of California San Diego and Ludwig Institute for Cancer Research. In 2019, Dr. Ly joined UT Southwestern Medical Center as an Assistant Professor in the Department of Pathology and CPRIT Scholar in Cancer Research. He holds a secondary appointment in the Department of Cell Biology and is a member of the Harold C. Simmons Comprehensive Cancer Center. The Ly Laboratory studies the causes and consequences of genomic instability in the context of cancer development. Cancer genomes are frequently characterized by extensive structural variation and DNA copy number alterations that can disrupt tumor suppressor genes, amplify oncogenes, and/or drive the formation of gene fusions. We are currently interrogating the factors that shape the chaotic mutational landscape of cancer genomes, including the contributions from cell cycle regulation defects, chromosome segregation errors during cell division, and inaccurate DNA double-strand break repair pathways.
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