Assistant Professor of Molecular Medicine
Cleveland Clinic's Lerner College of Medicine - CWRU
I completed my Undergraduate (B.Sc) and Masters (M.Sc) degrees in India with many academic accomplishments. For my graduate studies, I joined Dr. Bill Tansey’s laboratory at Cold Spring Harbor Laboratory (joint program with Stony Brook University), and studied the importance of Myc proteolysis in blood-borne cancers. I then moved to Boston for my post-doctoral research, where I trained under 2019 Physiology and Medicine Nobel Laureate, Dr. William Kaelin at the Dana-Farber Cancer Institute/Harvard Medical School. In Dr. Kaelin’s laboratory, I studied oxygen-sensing pathways, including the famous pVHL/HIF pathway, but also more generally how physiological oxygen regulates the function of the oxygen- and 2-oxo-glutarate dependent dioxygenase enzymes. I joined the faculty of the Cleveland Clinic in March 2019. The focus of my laboratory is to extend the studies linking dysfunctional oxygen-sensing pathways to epigenetic and metabolic consequences in kidney cancer. From this work, we hope to identify novel therapeutically targetable dependencies in kidney cancer.