Drug Effectiveness

(74) A Real-World Effectiveness of Second-Line Osimertinib in NSCLC Patients: A Multi-Institutions Study in Taiwan

(44) Association Between Sodium-Glucose Co-Transporter 2 Inhibitors and Heart Failure Readmission Among Patients with Type 2 Diabetes

(65) Biological Disease-Modifying Antirheumatic Drugs and Osteoporotic Fracture Risk in Patients with Rheumatoid Arthritis: A Danish Cohort Study with Prevalent New-User Design

(53) Cardiovascular Outcomes of GLP-1 Receptor Agonists Versus Metformin as First-Line Treatment for Type 2 Diabetes

(32) Characterizing Extension Studies in Interventional Research: Twenty Year Trends

(80) Comparative Effectiveness and Safety of First-Line Treatments of Metastatic Colorectal Cancer in Real-World Settings: A Systematic Review and Meta-Analysis

(49) Comparative Effectiveness and Safety of Sodium–Glucose Cotransporter 2 Inhibitors (SGLT2i) Versus Dipeptidyl Peptidase 4 Inhibitors (DPP-4i) in T2D Patients Across Different HbA1c Levels

(43) Comparative Effectiveness of Adjuvant Chemotherapy Versus Chemotherapy Plus Targeted Therapy After Resection of Both Primary Tumor and Metastases in Patient with Colorectal Cancer

(39) Comparative Effectiveness of Different Corticosteroid Regimens in Patients with Acute Respiratory Distress Syndrome

(83) Comparative Effectiveness of First-Line SGLT2 Inhibitor Use on Heart Failure Hospitalization Among Patients with Type 2 Diabetes Mellitus; A Target Trial Emulation

(75) Comparative Effectiveness of Regorafenib and Nivolumab as Sequential Therapies in Patients After Sorafenib Failure for Hepatocellular Carcinoma Patients: A Cohort Study in Taiwan

(33) Comparative Effectiveness of Sodium-Glucose Co-Transporter-2 Inhibitors Versus Dipeptidyl Peptidase-4 Inhibitors in Reducing Incidence of Stroke and Myocardial Infarction in Patients with Type 2 Diabetes

(85) Converging Evidence from Human Pharmacoepidemiology and Rodent Psychopharmacology Studies on the Role of Spironolactone as a Potential Pharmacotherapy for Alcohol Use Disorder

(55) Daily Tenofovir Disoproxil Fumarate/Emtricitabine and Hydroxychloroquine for Pre-Exposure Prophylaxis of COVID-19: A Double-Blind Placebo Controlled Randomized Trial in Healthcare Workers. A Randomized Clinical Trial

(88) Hemostatic Effectiveness of Four-factor Prothrombin Complex Concentrate for Treatment of Factor Xa Inhibitor-associated Acute Major Bleeds: A Meta-analysis

(76) Disease Relapse, Healthcare Utilization and Adverse Events Associated with The Use of Long-Acting Injectable Antipsychotics Versus Oral Antipsychotics in People with Schizophrenia: A Self-Controlled Case Series Study

(56) Drug Repurposing in a Pandemic: Systematic Review and Meta-Analysis of Randomized Trials of Hydroxychloroquine for the Prevention of COVID-19. What Have We Learned?

(AO) A Real-World Assessment of Sex Differences in The Comparative Safety and Effectiveness of Direct-Acting Oral Anticoagulants Versus Warfarin

(AH) Antipsychotic Polytherapy Versus Monotherapy in Specific Dose Categories in The Maintenance Treatment of Schizophrenia

(AJ) Association of Mortality by Statin Intensity in Chronic Liver Disease Patients with Atherosclerotic Cardiovascular Disease: A Nationwide Cohort Study

(AM) Comparative Effectiveness of Ticagrelor, Prasugrel, and Clopidogrel for Secondary Prophylaxis in Acute Coronary Syndrome

(AI) Comparative Risk of Opioid Overdose with Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants

(AK) Macrolide Treatment Failure Due to Drug-Drug Interactions: Real-World Evidence to Evaluate a Pharmacological Hypothesis

(AL) Real World Effects of Oral Anticoagulants in AF: A Cohort Study with Validation Against Results from a Randomised Controlled Trial

(AN) Real-World Evidence for The Effectiveness of Vitamin D Supplementation in The Reduction of Total and Cause-Specific Mortality. Results from Half a Million Participants of The UK Biobank Cohort Study

(50) Effect of Low-Dose Aspirin on The Primary Prevention of Colorectal Cancer in Patients with Type 2 Diabetes Taking Metformin

(31) Effect of Obeticholic Acid in Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) Patients: A Systematic Review and Meta-Analysis

(67) Effect of Statins on Coronary Artery Calcification: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(41) Effectiveness and Safety of Warfarin Use After Bariatric Surgery in Patients with Atrial Fibrillation and Venous Thromboembolism: A Real-World Analysis

(48) Efficacy and Safety of a Personalized Vitamin D3 Loading Dose Followed by 2,000 IU Per Day to Raise Serum 25-Hydroxyvitamin D Levels in Colorectal Cancer Patients with Vitamin D Insufficiency. Interim Analysis of a RCT

(79) Efficacy and Safety of Amphotericin B and Oral Miltefosine Combination in Patients with Visceral Leishmaniasis: A Systematic Review and Meta Analysis

(73) Efficacy and Safety of Baloxavir in The Treatment of Influenza: A Systematic Review and Meta-Analysis

(37) Efficacy and Safety of Corticosteroids in COVID-19: An Overview of Meta-Analyses

(81) Efficacy and Safety of Inhaled Corticosteroid Containing Combinations in Patients with Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review and Meta-Analysis

(36) Efficacy of Bictegravir /Emtricitabine/Tenofovir Alafenamide (B/F/TAF) Versus Dolutegravir Combinations in HIV-1 Adult Population: A Systematic Review and Meta-Analysis

(69) Evaluating Crisaborole 2% Ointment's Role in Improving Quality of Life in Patients Three Months and Older with Mild to Moderate Atopic Dermatitis: A Systematic Review

(82) High-Intensity Thromboprohylaxis Is Not Associated with Reductions in COVID-19 Worsening, Severe Disease, or Death

(47) Hospital Readmission and Mortality in Patients with Heart Failure Treated with Sacubitril/Valsartan versus Enalapril in Hong Kong

(64) Hydrochlorothiazide and Non-Melanoma Skin Cancer in Residents of the Province of Ontario, Canada

(84) Hydroxychloroquine for Pre-Exposure Prophylaxis of COVID-19 in Health Care Workers: A Randomized, Multicenter, Placebo-Controlled Trial (HERO-HCQ)

(42) Identifying Factors with and Effects of Metformin on The Risk of Alzheimer's Disease and Other Dementias: A Machine Learning Approach

(46) Impact of Romosozumab on Bone Mineral Density in Postmenopausal Osteoporosis

(60) Inhaled Corticosteroid Combinations in COPD-Safety and Efficacy: A Systematic Review of Real-World Data

(34) Jak Inhibitors for Atopic Dermatitis: A Network Meta-Analysis of Adverse Events

(70) Long-Term Relative Effectiveness of Anti-Hypertensive and Anti-Hyperlipidemic Drug Monotherapy in Primary Prevention of Cardiovascular Events

(78) Medication Self-Management in Hospitalised Patients with Schizophrenia or Bipolar Disorder: The Perceptions of Patients and Healthcare Providers

(35) Numbers Needed to Treat to Benefit (NNTB) and to Harm (NNTH) for COVID-19 Medicines

(63) Potential Unknown Benefits of Rabeprazole: Real-World Evidence Generated Using the REWARD Framework

(62) Prevalence of Use of GABA Receptor Positive Allosteric Modulator Use and Associations with Treatment Discontinuation Among Patients Receiving Cancer Immunotherapy

(72) Real World Effectiveness of Lipid-Lowering Medication in Denmark

(71) Real-World Effectiveness and Safety of Ramucirumab in Hepatocellular Carcinoma Patients: A Retrospective Study in Taiwan

(68) Real-World Effectiveness of Methadone Maintenance Treatment on The Reduction of Suicidal Attempts in Patients with Opioid Use Disorder

(77) Real-World Impact of Non-Clinical Inhaler Switching on Asthma or COPD Patients: A Systematic Review

(66) Restricted Mean Survival Time for Analysis of Real-World Cardiovascular Effect Associated with SGLT2 Inhibitor Use: A Population-Based Study

(59) Risk of Falls and Fractures with Concomitant Use of Prescription Opioids and Other Medications in Osteoarthritis Patients

(45) Safety and Efficacy of Perampanel in Epilepsy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

(40) Sociodemographic Factors and Medications for Opioid Use Disorder (MOUD) Initiation and Retention: A Review

(54) Sodium Glucose Cotransporter 2 Inhibitors and The Risk of Respiratory Outcomes Among Patients with Type 2 Diabetes: A Nationwide Cohort Study

(86) Sodium-Glucose Cotransporter-2 Inhibitors and The Risk of Lung Cancer Among Patients with Type 2 Diabetes

(52) Statins and LDL-Cholesterol Control in The Long-Term: A Retrospective Cohort Study Using Electronic Health Records

(57) Survival Analysis of Riluzole for Patients with Motor Neuron Disease in Hong Kong: A Population-Based Cohort Study

(38) The Association Between Antihypertensive Agents and Incident Alzheimer's Disease: A Systematic Review and Meta-Analysis of Observational Studies

(61) The Impact of Expanded Access to Direct Acting Antivirals for Hepatitis C on Patient Outcomes in Canada

(303) Antithrombotic use decreases the risk of mortality due to COVID-19 of nursing home residents during the first wave

(87) Use of Immunosuppressive Drugs (ISD) and The Effectiveness of Immune Checkpoint Inhibitor (ICI) Therapy Among Patients with Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) in the United States (US)

(58) Use of Riluzole and Risk of Hospitalization for Patients with Motor Neuron Disease in Hong Kong: A Self-Controlled Case Series Study