.jpg "Rahul S. Samant, PhD photo")
Tenure-Track Group Leader
Babraham Institute
Cambridge, England, United Kingdom
Rahul has studied stress signaling and proteostasis throughout his PhD and postdoctoral training, and is building upon this expertise in his group at the Babraham Institute (Cambridge, UK). After completing his undergraduate studies in Natural Sciences (Biochemistry) at University of Cambridge (2004-2007), he did his PhD in Paul Workman's group at The Institute of Cancer Research (2007-2011), where he investigated the role of ubiquitylation machineries in the degradation of oncogenic protein kinase degradation upon inhibition of the molecular chaperone HSP90. Following a short postdoc carrrying on this work, he moved to California in 2014 to start a postdoc in Judith Frydman's lab (Stanford University). Here, he used the model organism S. cerevisiae to expand understanding of the molecular circuits involved in misfolded protein clearance, and how these vary depending on their sub-cellular localisation.
Rahul start as a Tenure-Track Group Leader at Babraham Institute in 2019. His group uses a combination of mass spectrometry-based proteomics, super-resolution imaging, and bespoke biochemical tools to tease apart how communication between protein degradation systems contributes to healthy proteostasis, and how this goes awry during ageing and associated stresses. Much of his group currenlty focuses on the interplay between loss of proteostasis and cellular senescence as two hallmarks of ageing.
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Sunday, November 6, 2022
10:00 AM – 11:30 AM ET
Sunday, November 6, 2022
10:00 AM – 11:30 AM ET