Vice Chair for Research and Professor
Saint Louis University School of Medicine
St. Louis, Missouri, United States
My research has focused on psychiatric and clinical epidemiology. During the first 10 years of my career as a faculty member at Washington University School of Medicine, Department of Psychiatry, I worked in twin studies and the etiology and patterns of comorbid psychiatric and substance use disorder, including alcohol misuse and use disorder, Since 2008 I have focused on funded research in clinical epidemiology. I have a track record of applying advanced methods to administrative medical record and medical claims data to a wide range of research questions and content areas. In my Veterans Health Administration (VA) Career Development Award, I used a large VA administrative medical record data base to study the relationship between depression, anxiety disorders and incident myocardial infarction. In VA and private sector cohorts, I then conducted numerous studies on prescription opioid pharmaco-epidemiology and the association between chronic opioid use and dose and new onset and worsening depression (R21MH101389). This retrospective cohort study has now been expanded to a prospective cohort of new opioid users to determine moderators of the association between chronic prescription opioid use and incident depression (R01DA043811). I completed a study of metformin and risk for dementia (R21AG055604) using big medical record data bases and I have completed a Benter Foundation award to investigate potential protective effects of adult vaccinations on incident dementia in a VA cohort with replication in a MarketScan claims data base. I have also recently completed a study of the effects of PTSD, PTSD psychotherapy and poor health behaviors, incident cardiovascular and metabolic disease (R01HL125424) using VA administrative data.
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Friday, November 4, 2022
12:00 PM – 1:30 PM ET
Friday, November 4, 2022
12:00 PM – 1:30 PM ET