Professor of Medicine
Ragon Institute of MGH, Harvard and MIT, Cambridge, MA, USA
Cambridge, Massachusetts, United States
Shiv Pillai MD PhD is a Professor of Medicine and Health Sciences and Technology at Harvard Medical School. He is the director of the Harvard PhD and MMSc Immunology programs and of the HMS-HST MD student research program. He is also the program director of an NIH-funded Autoimmune Center of Excellence at Massachusetts General Hospital. Dr. Pillai coined the term “surrogate light chains” for proteins that he identified as part of the pre-B receptor, that drives early B cell development. His laboratory postulated and provided evidence for the first ligand-independent signaling model during lymphocyte development and showed that BTK, the product of the gene mutated in X-linked agammaglobulinemia, is functionally linked to the pre-B receptor and the B cell receptor. Btk inhibitors are now widely used in lymphoid malignancies and autoimmunity His laboratory is currently located at the Ragon Institute and his group studies T cell-B cell collaboration and its relevance to autoimmune and inflammatory diseases including IgG4-related disease, systemic sclerosis, common variable immunodeficiency and COVID-19. He has been the recipient of a number of teaching awards at Harvard including the Irving M. London Award for Teaching and the Thomas McMahon Mentoring Award. Dr. Pillai is the author of a monograph "Lymphocyte Development" and co-author with Abul Abbas and Andrew Lichtman of two widely used textbooks of immunology.
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Monday, June 20, 2022
8:00 AM – 5:30 PM PT
Thursday, June 23, 2022
2:05 PM – 2:30 PM PT
