This on-demand Symposium covers the most recent evidence on the immune responses that safeguard barrier integrity. The interplay between immune cells and microbiota will be discussed, focusing on compartmentalized interactions and exploring the crosstalk between distant districts (gut, liver, brain, lung). Dysfunctions of barrier immunity will be highlighted in autoimmunity, asthma, and infections, and vaccinal strategies rescuing barrier integrity will be discussed.
Chair: Raffaele De Palma, MD, PhD University of Genoa (Italy)
Program Agenda: Microbiota and Immune System in Gut-Liver-Brain Axis Prof. Maria Rescigno, PhD Humanitas University (Italy)
Role of Gut Microbiota in Autoimmune Diabetes Prof. Agnes Lehuen, PhD Institut Cochin (France)
Relationship Between Intestinal and Pulmonary Microbiome Dysbiosis in Asthma Prof. Erika Jensen-Jarolim, MD Medical University of Vienna (Austria)
Maladapted Antibacterial Epithelial Response in the Post-influenza Lung as a Potential Driver for Enhanced Susceptibility to Bacterial Superinfection Prof. Dunja Bruder, PhD Helmholtz Centre for Infection Research (Germany)
Novel Vaccines Targeting DCs for Allergic and Infectious Diseases to Restore Inflammation and Barriers Integrity Prof. Oscar Palomares Gracia, PhD Universidad Complutense de Madrid (Spain)
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