Turning It Up and Turning It Down – Regulating Immune Responses in Mucosal Tissues

Description:
The immune system in mucosal tissues needs to provide protection against infection without causing excessive tissue damage upon activation. The immune system is also involved in restoring tissue homeostasis and tissue healing. In this symposium, the speakers will discuss the interactions and mechanisms that orchestrate immune responses and function in mucosal tissues. The speakers will discuss the consequences of immune cell activation in context of pathogen control and tissue pathology. The speakers will also present new technologies for assessing mucosal tissue-based immune responses. Overall, the topics of these talks will be of interest to a wide audience that includes clinicians as well as basic immunologists.

Chair:
Martin Prlic, PhD
Fred Hutch Cancer Research Center

Program Agenda:
1:00pm -1:35pm
Disentangling Human Tumor Immune Alterations from Non-malignant (Mucosal) Tissue Inflammation
Martin Prlic, PhD
Fred Hutch Cancer Research Center

1:35pm -2:10pm
Migratory ILC2s: Small in Number but Large in Purpose
R. Lee Reinhardt, PhD
National Jewish Health

2:10pm - 2:45pm
Regulatory T Cell Therapy for IBD
Megan Levings, PhD
The University of British Columbia

2:45pm - 3:15pm
Break

3:15pm - 3:50pm
The Role of Decidual Lymphocyte and Trophoblast Interactions in Maternal-Fetal Tolerance and Immunity
Tamara Tilburgs, PhD
Cincinnati Children's Hospital

3:50pm - 4:25pm
To Be Announced
Mitchell Kronenberg, PhD
La Jolla Institute for Immunology