Track: BIOCHEMISTRY AND MOLECULAR BIOLOGY
Mary Dasso
Presenting Author
National Institute of Child Health and Human Development
This workshop seeks to bring together different emerging approaches and model systems that are being applied to untangle the sequence and logic of RNA processing and export events. The focus of this Workshop will be on nuclear pore proteins as guardians of mRNA export and their role in the selectivity of RNA export in health and disease. The workshop will bring together laboratories using cryo-EM, X-ray crystallography, biochemistry, nuclear microinjection, genetics, cell biology, CRISPR/Cas9-AID gene editing, live imaging, viral and animal models to elucidate interactions between nucleoporins, mRNA, and RNA-accessory proteins at the NPC. Attendees will learn about cutting-edge tools and techniques and their application to the process of mRNA export. They will learn up-to-date progress, unresolved questions in the field and meet world class experts.
Who should attend: This workshop will appeal to a diverse group of scientists (students, postdoctoral researchers and group leaders) who are interested in RNA processing and export, the regulation of gene expression, nuclear trafficking and nucleoporins.
Presenters:
Mary Dasso, Division of Molecular and Cellular Biology, NICHD, NIH
Vasilisa Aksenova, NIH, NICHD
Yi Ren, Vanderbilt University
Beatriz Fontoura, UT Southwestern
Katherine Borden, Universite de Montreal
Alexander F. Palazzo, University of Toronto, Canada