397 - Metabolic mechanisms

Session Chair(s)

• Scott Dixon

  Presenting Author
  Stanford University

Metabolism is complex and dynamic, involving hundreds of enzymes and reactions. Versions of many enzymes are found in most living organisms on earth. In development, metabolic processes are central for growth; in diseased tissues, metabolism is altered and contributes to pathology. Symbiotic or competitive metabolic interactions between organisms govern a broad swath of important biology in the immune system and gut. How these interactions are regulated by and coordinated with DNA-based, RNA-based and protein-based mechanisms remains under investigation. The metabolism field continues a rapid expansion. This session will explore a breadth of models and approaches being used to investigate how metabolism impacts development, homeostasis, disease and medicine.

Who should attend: anyone interested in learning how metabolism impacts development, disease or therapy.

Presentations:

• 9:15 AM – 9:45 AM

  Lipid Metabolism and Ferroptosis
  

  Presenting Author: Scott Dixon – Stanford University
• 9:45 AM – 10:15 AM

  Too much and never enough: Synthetic excess and metabolic inefficiency of aneuploidy in tumorigenesis
  

  Presenting Author: Emma Watson – Brigham and Womens Hospital
• 10:15 AM – 10:45 AM

  Uncovering conditional vulnerabilities in human cancer cells
  

  Presenting Author: Jason Cantor – Morgridge Institute for Research (University of Wisconsin-Madison)
• 10:45 AM – 11:15 AM

  The genetics of tumor suppression by p53
  

  Presenting Author: Maureen Murphy – The Wistar Institute