51 - Liver Pathobiology: Therapeutics and Pathway Targets

Session Chair(s)

• Sharon DeMorrow

  Presenting Author
  The University of Texas at Austin, Central Texas Veterans Healthcare System

• Heather Francis

Presentations:

• 2:00 PM – 2:15 PM

  Suppression of MT1 and Melatonin Treatment Improves Liver Phenotypes in Mdr2-/- mice
  

  Presenting Author: Ludovica Ceci – Gastroenterology, Medicine, Indiana University,
• 2:15 PM – 2:30 PM

  Investigating Susceptibility of ꞵ-catenin-mutated Hepatocellular Carcinoma to Checkpoint Inhibitors
  

  Presenting Author: Evan Delgado – University of Pittsburgh
• 2:30 PM – 2:45 PM

  Therapeutic implication of SOX9 and YAP1 co-repression in advanced intrahepatic cholangiocarcinoma
  

  Presenting Author: Shikai Hu – Tsinghua University, University of Pittsburgh
• 2:45 PM – 3:00 PM

  Regulation of Transplanted Fetal Hepatocyte Proliferation by Histone Post-Translational Modifications
  

  Presenting Author: Anders Ohman – Brown University, Rhode Island Hospital
• 3:00 PM – 3:15 PM

  Use of Nucleoside Modified mRNA Encoding Regenerative Factors Encapsulated with Lipid Nanoparticles to Alleviate Acute and Chronic Murine Liver Diseases
  

  Presenting Author: Valerie Gouon-Evans – Boston University
• 3:15 PM – 3:30 PM

  A PanFzd receptor agonist induces β-catenin activation to promote hepatic repair after surgical and acetaminophen-induced injury
  

  Presenting Author: Shikai Hu – Tsinghua University, University of Pittsburgh
• 3:30 PM – 3:45 PM

  Targeting Galanin Receptor Signaling as a Novel Therapeutic Strategy for the Treatment of Fatty Liver Disease
  

  Presenting Author: Sharon DeMorrow – The University of Texas at Austin, Central Texas Veterans Healthcare System
• 4:00 PM – 4:15 PM

  Enabling regeneration in a β-catenin-deficient liver: Unraveling a novel compensatory role of mTOR
  

  Presenting Author: Shikai Hu – Tsinghua University, University of Pittsburgh
• 4:15 PM – 4:30 PM

  Inhibition of Ileal Bile Acid Transport is Protective Against Cholestatic Liver Injury in Cyp2c70-/-Mice with Humanized Bile Acid Composition
  

  Presenting Author: Jennifer Truong – Emory University School of Medicine
• 4:30 PM – 4:45 PM

  Understanding Molecular Heterogeneity in Hepatocellular Carcinoma
  

  Presenting Author: Evan Delgado – University of Pittsburgh
• 4:45 PM – 5:00 PM

  Role of Jak3 in cross talk between Intestinal and biliary epithelial cells
  

  Presenting Author: Narendra Kumar – Texas A&M University, Texas A&M University