9 - Advances in Liver Homeostasis and Repair

Session Chair(s)

• George Michalopoulos

• Chhavi Goel

  Presenting Author
  University of Pittsburgh

Presentations:

• 8:30 AM – 8:45 AM

  Inhibiting TET1 alleviates non-alcoholic liver disease progression by targeting lipid metabolic pathways.
  

  Presenting Author: Joud Mulla – Alpert Medical School Brown University
• 8:45 AM – 9:00 AM

  Revealing novel molecular pathways in exosome production and pathological effects in the context of autophagy deficiency
  

  Presenting Author: Gang Liu – Tulane University
• 9:00 AM – 9:15 AM

  Loss of SQSTM1/p62 Induces Obesity and Exacerbates Alcohol-induced Liver Injury in Aged Mice
  

  Presenting Author: Hui Qian – University of Kansas Medical Center
• 9:15 AM – 9:30 AM

  Beta-catenin inhibition as a novel therapeutic strategy for porphyria
  

  Presenting Author: Anu Balogun – University of Pittsburgh
• 9:30 AM – 9:45 AM

  Loss of hepatic mTORC1 signaling affects liver homeostasis which is partially compensated by Wnt/β-catenin pathway activation
  

  Presenting Author: Shikai Hu – Tsinghua University, University of Pittsburgh
• 9:45 AM – 10:00 AM

  Single-cell spatial transcriptomics analysis of a regenerating liver
  

  Presenting Author: Satdarshan (Paul) Singh Monga – University of Pittsburgh
• 10:00 AM – 10:15 AM

  Inhibition of Phosphoinositide 3-kinase delta (PIK3CD) Suppresses Hepatocyte Proliferation by More than 50% in the Regenerating Liver after Partial Hepatectomy
  

  Presenting Author: Nicole Martucci – University of Pittsburgh
• 10:15 AM – 10:30 AM

  β-catenin Overexpressing Hepatocytes Reduce Bile Stasis by Contributing to Cholangiocyte-Like Phenotype in Murine Model of Intrahepatic Cholestasis
  

  Presenting Author: Chhavi Goel – University of Pittsburgh
• 10:30 AM – 10:45 AM

  The Unfolded Protein Response Regulates ER-phagy in Fibrogenic Hepatic Stellate Cells
  

  Presenting Author: Zachary Hanquier – Indiana University School of Medicine
• 10:45 AM – 11:00 AM

  Hepatic Neddylation Deficiency Triggers Fatal Liver Injury via Inducing NF-κB-inducing Kinase and Oxidative Stress
  

  Presenting Author: Weiqin Chen – Augusta University