392 - Physiological and pathological phase transitions of disordered proteins

Session Chair(s)

• Tanja Mittag

  Presenting Author
  St. Jude Childrens Research Hospital

In this session, we will highlight the spectrum between ordered molecular machines with precise stoichiometry and nonstoichiometric condensates, the latter of which can be disordered completely or have a more defined network structure. Both are necessary and shape functions in our cells.

Who should attend: everyone who likes molecular mechanisms and is not afraid of a bit of disorder.

Presentations:

• 9:15 AM – 9:55 AM

  Phase behavior of intrinsically disordered prion-like domains
  

  Presenting Author: Tanja Mittag – St. Jude Childrens Research Hospital
• 9:55 AM – 10:35 AM

  Liquid-liquid phase separation modulated by post-translational modifications and its implications for gene regulation
  

  Presenting Author: Tae Hun Kim – Hospital for Sick Children
• 10:35 AM – 11:15 AM

  Polyubiquitin effects on phase transitions of shuttle protein UBQLN2
  

  Presenting Author: Carlos Castaneda – Syracuse University