376 - Mechanisms of Liver Injury

Session Chair(s)

• Xiao-Ming Yin

• Laura Molina

  Presenting Author
  University of Pittsburgh School of Medicine

Presentations:

• 8:30 AM – 8:45 AM

  Loss of hepatic Drp1 contributes to alcohol-induced megamitochondria and exacerbates alcoholic hepatitis via impaired mitophagy and mitochondrial lipid oxidation
  

  Presenting Author: Xiaowen Ma – The University of Kansas Medical Center
• 8:45 AM – 9:00 AM

  A Novel Murine Model for Studying Alcohol-associated Biliary Dysfunction
  

  Presenting Author: Shengmin Yan – Tulane University School of Medicine
• 9:00 AM – 9:15 AM

  Mast Cell (MC)-Induced Cholestasis is Dependent on Apical Sodium Bile Acid Transporter (ASBT) Expression
  

  Presenting Author: Vik Meadows – Indiana University School of Medicine
• 9:15 AM – 9:30 AM

  The protective effects of estrogen on biliary and liver damage are independent of ER-β signaling in female Mdr2-/- mice
  

  Presenting Author: Travis Owen – Indiana University School of Medicine
• 9:30 AM – 9:45 AM

  In the Absence of YAP, TAZ Contributes to Hepatocyte Adaptation in Chronic Cholestasis in Females
  

  Presenting Author: Laura Molina – University of Pittsburgh School of Medicine
• 9:45 AM – 10:00 AM

  METTL3 Enhances Hepatocellular Carcinoma Progression by Regulating Polycomb Repressive Complex 1 (PRC1) Components BMI1 and RNF2
  

  Presenting Author: Weina Chen – Tulane University
• 10:00 AM – 10:15 AM

  Characterization of Hepatic Injury During the Azoxymethane Model of Acute Liver Failure
  

  Presenting Author: Matthew McMillin – University of Texas at Austin, Central Texas Veterans Health Care System
• 10:15 AM – 10:30 AM

  Hyperammonemia-induced DNA-damage Response Leads to the Acquisition of Cellular Senescence in Neurons after Chronic Liver Failure
  

  Presenting Author: Elaina Williams – University of Texas at Austin
• 10:30 AM – 10:45 AM

  Conjugated Bile Acids activate Reactive Oxygen Species-p90RSK-Vascular Endothelial Growth Factor Receptor 3 signaling axis to promote lymphangiogenesis
  

  Presenting Author: Priyanka Banerjee – Texas A&M Health Science Center
• 10:45 AM – 11:00 AM

  Lipocalin-2 Stimulates Proliferation and a Profibrotic Cholangiocyte Phenotype during Cholestasis
  

  Presenting Author: April OBrien – Texas A&M Health Science Center