155.4 - Social Interactions as Alternative to Drug Use and Craving
Sunday, April 3, 2022
2:58 PM – 3:23 PM
Room: 113 C - Pennsylvania Convention Center
Introduction: Although standard intravenous drug self-administration procedures remain the gold-standard for assessing the abuse potential of psychoactive drugs, substance use disorders (SUDs) are complex, multifaceted, and not fully recapitulated by any single animal model. Recently, novel behavioral paradigms have been developed to model specific aspects of SUD to better understand the neurobiology of individual vulnerabilities to develop SUD-related behaviors, and to evaluate candidate medications for treating SUDs. After a brief introduction on the use of animal models of SUDs, three speakers will discuss their research evaluating SUD-related phenotypes in rats, the use of drug-food choice procedures, and a social-operant choice assay.
