424.2 - Disabling Gβγ-SNARE Interaction Disrupts GPCR-mediated Presynaptic Inhibition Leading to Physiological and Behavioral Phenotypes
Tuesday, April 5, 2022
2:02 PM – 2:20 PM
Room: 113 A - Pennsylvania Convention Center
Introduction: This session will focus on recently identified roles of G protein signaling components in brain disorders, pointing to novel therapeutic pathways. Translational studies highlight the essential role of regulator of G protein signaling 4 in the maintenance of chronic pain states, the importance of spinophilin/coffilin interaction in post traumatic stress disorders, the impact of striatal cAMP signaling components on movement disorders and the impact of Gβγ–SNARE interaction on restoration of the release of hormones and neurotransmitters.
