88.3 - Effect of COVID-19 Infection on the Innate Immune System and the Disposition of Complex Drugs
Sunday, April 3, 2022
8:30 AM – 8:55 AM
Room: 113 A - Pennsylvania Convention Center
Introduction: Acute infection and inflammation transiently suppress hepatic drug metabolism. This session will discuss clinical cases supporting altered pharmacokinetics of small molecules and biologics following SARS-CoV-2 infection or immunization and examine the mechanisms of interactions between the innate immune response and small molecule and biologic metabolism following SARS-CoV-2 infection or immunization. Understanding the impact of emerging infections and vaccine technologies on drug metabolism will help mitigate drug toxicity and improve drug and vaccine safety and effectiveness.
William Zamboni ( University of North Carolina - UNC Eshelman School of Pharmacy )
